Policy base for activity therapy:
For people with cardiovascular disease.
National Institute for Health and Care Excellent (NICE):
NICE recommends structured exercise programmes tailored to individual need to manage, and for rehabilitation after, certain health conditions, including:
· myocardial infarction (see NICE clinical guideline 172 on secondary prevention)
· stroke (see NICE clinical guideline 162 on rehabilitation)
· chronic heart failure (see NICE clinical guideline 108)
Moving Medicine/The Faculty of Sport and Exercise Medicine:
From the Faculty:
There is a small risk associated with increasing exercise levels but the Faculty of Sport and Exercise Medicine Guidelines on the balance of risks and benefits of activity for people with Cardiac Chest Pain states that:
“The balance of evidence suggests that the long-term benefits of increasing levels of regular physical activity far outweigh the temporary slightly increased risk of adverse events when those with ischaemic heart disease. This risk increases with advancing age and exercise intensity, but overall remains very low.
People should be counselled individually to gradually increase physical activity, taking into account severity of symptoms, fear of cardiac chest pain and red flag symptoms.”
From Moving Medicine:
Brisk walking can be easily incorporated into everyday life for many people and is an acceptable form of physical activity.
The least active individuals stand to gain the most from a small increase in physical activity.
The Academy of Medical Royal Colleges’ Report:
“All studies show clear improvements in cardiovascular health with moderate exercise. There are similar beneficial effects for sufferers of angina. 27 Overall, exercise reduces cardiac mortality by 31%.”
The medical team at the British Heart Foundation:
Physical activity can help reduce your risk of heart and circulatory disease. It can also help you control your weight, reduce blood pressure and cholesterol and improve your mental health.
Condition:
Cardiovascular disease (including previous heart attack/myocardial infarction, coronary heart disease, heart failure and atrial fibrillation).
Definition:
The cardiovascular system consists of the heart and the arteries which carry oxygen rich blood to the tissues of the body, and the veins which carry blood back from the tissues to be circulated through the lungs to discharge carbon dioxide, and absorb fresh oxygen.
The basic problem is usually a disease of the arteries called atherosclerosis which is a build up of fatty tissues in the walls of the arteries, like water pipes furring up, and makes them more likely to become blocked by a blood clot.
Organising the evidence base for cardiovascular disease is more complicated than organising the evidence base for cancer. Most people with cancer have just one cancer and activity seems to have the same effect on different types of cancer but ‘cardiovascular disease’ is a very broad concept. It includes both heart disease – cardio- arterial – vascular – disease and of course the most common cause of heart disease is disease of the arteries of the heart the coronary arteries. There are two other major arterial diseases, affecting the brain – stroke – and of the lower limbs -peripheral arterial disease - and these are dealt with separately.
The term Cardio of course relates to the heart as indeed does the term Coronary and the term Coronary Heart Disease is a tautology but it is widely used in the scientific literature for problems caused by disease of the coronary arteries, the arteries that supply the heart muscle itself as distinct from, for example, congenital heart disease. There are other causes of heart disease but disease caused by atherosclerosis of the coronary arteries is by far the most common type and the term Ischaemic Heart Disease meaning disease caused by reduction of the oxygen supply due to narrowing of the arteries .
Heart disease may present as an acute myocardial infarction or as recurrent chest pain on exercise, called angina. It is now standard practice for people who have had a myocardial infarction, usually treated with a stent, to be referred to a cardiac rehabilitation clinic in a local gym before they have left hospital. People with angina should not be advised to increase their activity unless it is guided by a specialised cardiac rehabilitation team because it is the acute phase of a disease and as a general rule exercise is not indicated in the acute phase of a disease. When a person has had treatment, a stent or surgery, then exercise will be organised in the immediate period after the treatment in a cardiac rehabilitation services, often in a nearby gym, but they also need to be helped to change their lifestyle to increase their own activity levels for the rest of their life.
People who are told they have heart disease or coronary heart diseases may have no symptoms after they have had an operation or a stent but they may develop complications of which the two most common are atrial fibrillation and heart failure so we have searched using these two terms although there is an overlap between the results of the three searches and it is important to understand that the way in which papers are coded and classified is not a precise science.
Cause and scope for prevention From the Faculty:
The causes of atherosclerosis or heart disease are now relatively well known:
· Smoking
· An imbalance between energy intake and output resulting in obesity
· Changes in the blood chemistry with increased glucose, lipids and cholesterol and these are sometimes diagnosed as hypercholesterolaemia, metabolic syndrome, or hyperlipidaemia
· Lack of exercise
Diagnosis:
Usually the person presents with chest pain and diagnosis is by imaging, sometimes with direct visualisation of the arteries.
Standard Medical Therapy:
Drug treatment sometimes with the insertion of a stent—a small tube pushed through the narrowed blood vessel. It is important to recognise that standard medical therapy for people who have had a heart attack now includes referral to an exercise programme, often called cardiac rehabilitation.
Benefit of exercise therapy:
Exercise directly affects the process of atherosclerosis and therefore stops the condition getting worse. The Academy of Medical Royal Colleges report on Exercise—The Miracle Cure, states:
“All studies show clear improvements in cardiovascular health with moderate exercise. There are similar beneficial effects for sufferers of angina. 27 Overall, exercise reduces cardiac mortality by 31%.”
In addition exercise:
· Helps the person feel better and reduces depression
· Increases fitness and ability, closing the fitness gap
· Reduces the risk of other conditions such as dementia
Search strategy:
We search the National Library of Medicine for systematic reviews (see Appendix 1 for a definition). We also specifically identify the Cochrane Reviews because Cochrane is committed to their regular updating.
We review the titles of the last five years because some of them have been given the wrong keyword and do not relate to exercise therapy. We only search the last five years because we have Exercise the Miracle Cure, published in 2015 as a comprehensive account of the evidence at that time.
This produces a list of relevant reviews.
Condition: People with Coronary Heart Disease:
Number of systematic reviews (15-01-2021): 224
Number of these that are Cochrane reviews: 96
Number of systematic reviews in the last five years: 110
Number of systematic reviews in last five years deemed irrelevant: 35
Number of systematic reviews in the last five years deemed relevant APPENDIX 2: 75
Condition: People with Atrial Fibrillation:
Number of systematic reviews (15-01-2021): 43
Number of these that are Cochrane reviews: 2
Number of systematic reviews in the last five years: 20
Number of systematic reviews in last five years deemed irrelevant: 7
Number of systematic reviews in the last five years deemed relevant APPENDIX 3: 13
Condition: People with Heart Failure:
Number of systematic reviews (15-01-2021): 322
Number of these that are Cochrane reviews: 171
Number of systematic reviews in the last five years: 176
Number of systematic reviews in last five years deemed irrelevant: 81
Number of systematic reviews in the last five years deemed relevant APPENDIX 4: 95
Condition: People with Angina:
Number of systematic reviews (15-01-2021): 62
Number of these that are Cochrane reviews: 39
Number of systematic reviews in the last five years: 28
Number of systematic reviews in last five years deemed irrelevant: 18
Number of systematic reviews in the last five years deemed relevant APPENDIX 5: 10
Exercise Benefits Coronary Heart Disease.
The role of cardiac rehabilitation in patients with heart disease.
Key organisations:
In preparing a systematic review the reviewer:
1. Prepares a protocol conforming to one of the standard protocols eg that of Cochrane.
2. Defines a search strategy with the support of a librarian.
3. Uses explicit quality criteria to include or exclude primary studies.
4. Combines the data from the primary studies (a process called meta-analysis).
5. Prepares a report including the references to the excluded studies as well as to the included studies.
The term ‘overview of systematic reviews’ describes an article in which all the available systematic reviews are combined.
Exercise therapy for people with Cardiovascular Disease
METHOD
The National Library of Medicine www.nlm.gov was searched for ‘Systematic Review’, in the last 5 years. 110 reviews were identified.
These were reviewed by Muir Gray for relevance eg some systematic reviews were focused on drug therapy, this removed 35 reviews from the database and the remaining 75 are listed below.
USING THE DATABASE
To read the abstract or the full text simple copy the doi, for example
doi: 10.1016/j.bjpt.2017.06.004. and paste it into your web browser.
1
Effects of Exercise after Percutaneous Coronary Intervention on Cardiac Function and Cardiovascular Adverse in Patients with Coronary Heart Disease: Systematic Review and Meta-Analysis.
Zhang H, Chang R.
J Sports Sci Med. 2019 Jun 1;18(2):213-222. eCollection 2019 Jun.
PMID: 31191090 Free PMC article.
2
High-intensity interval training versus moderate-intensity continuous training on exercise capacity and quality patients with coronary artery disease: A systematic review and meta-analysis.
Gomes-Neto M, Dur.es AR, Reis HFCD, Neves VR, Martinez BP, Carvalho VO.
Eur J Prev Cardiol. 2017 Nov;24(16):1696-1707. doi: 10.1177/2047487317728370. Epub 2017 Aug 21.
PMID: 28825321 Review.
3
Patient education in the management of coronary heart disease.
Anderson L, Brown JP, Clark AM, Dalal H, Rossau HK, Bridges C, Taylor RS.
Cochrane Database Syst Rev. 2017 Jun 28;6(6):CD008895. doi: 10.1002/14651858.CD008895.pub3.
PMID: 28658719 Free PMC article. Review.
4
A systematic review of effects of recorded music listening during exercise on physical activity adherence and outcomes in patients with coronary heart disease.
Chair SY, Zou H, Cao X.
Ann Phys Rehabil Med. 2020 Nov 15dS1877-0657(20)30192-5. doi: 10.1016/j.rehab.2020.09.011. Online ahead of print.
PMID: 33130038 Review.
5
The effect of progressive resistance training on aerobic fitness and strength in adults with coronary heart disease
systematic review and meta-analysis of randomised controlled trials.
Hollings M, Mavros Y, Freeston J, Fiatarone Singh M.
Eur J Prev Cardiol. 2017 Aug;24(12):1242-1259. doi: 10.1177/2047487317713329. Epub 2017 Jun 5.
PMID: 28578612 Review.
6
A systematic review of recent cardiac rehabilitation meta-analyses in patients with coronary heart disease or
failure.
Oldridge N, Pakosh M, Grace SL.
Future Cardiol. 2019 May;15(3):227-249. doi: 10.2217/fca-2018-0085. Epub 2019 Jun 4.
PMID: 31161796
7 Telehealth exercise-based cardiac rehabilitation: a systematic review and meta-analysis.
Rawstorn JC, Gant N, Direito A, Beckmann C, Maddison R.
Heart. 2016 Aug 1;102(15):1183-92. doi: 10.1136/heartjnl-2015-308966. Epub 2016 Mar 2.
PMID: 26936337 Review.
Page 2
9
PEDro systematic review update: exercise for coronary heart disease.
Deveza RC, Elkins M, Saragiotto BT.
Br J Sports Med. 2017 May;51(9):755-756. doi: 10.1136/bjsports-2016-096864. Epub 2016 Oct 27.
PMID: 27789431 Review. No abstract available.
10
Effects of rehabilitation exercise on coronary artery after percutaneous coronary intervention in patients with
coronary heart disease: a systematic review and meta-analysis.
Fu C, Wang H, Wei Q, He C, Zhang C.
Disabil Rehabil. 2019 Dec;41(24):2881-2887. doi: 10.1080/09638288.2018.1481148. Epub 2018 Jul 10.
PMID: 29991296
11
High-intensity Interval Training Dosage for Heart Failure and Coronary Artery Disease Cardiac Rehabilitation. Systematic Review and Meta-analysis.
Ballesta Garc.a I, Rubio Arias J., Ramos Campo DJ, Mart.nez Gonz.lez-Moro I, Carrasco Poyatos M.
Rev Esp Cardiol (Engl Ed). 2019 Mar;72(3):233-243. doi: 10.1016/j.rec.2018.02.015. Epub 2018 Apr 9.
PMID: 29650445 English, Spanish.
12
Cardiac rehabilitation and physical activity: systematic review and meta-analysis.
Dibben GO, Dalal HM, Taylor RS, Doherty P, Tang LH, Hillsdon M.
Heart. 2018 Sep;104(17):1394-1402. doi: 10.1136/heartjnl-2017-312832. Epub 2018 Apr 13.
PMID: 29654095 Free PMC article.
13 Cost-effectiveness of exercise therapy in patients with coronary heart disease, chronic heart failure and risk factors: A systematic review of economic evaluations of randomized clinical trials.
Oldridge N, Taylor RS.
Eur J Prev Cardiol. 2020 Jul;27(10):1045-1055. doi: 10.1177/2047487319881839. Epub 2019 Oct 26.
PMID: 31657233
14
Minimal clinically important difference for change in 6-minute walk test distance of adults with pathology: a systematic review.
Bohannon RW, Crouch R.
J Eval Clin Pract. 2017 Apr;23(2):377-381. doi: 10.1111/jep.12629. Epub 2016 Sep 4.
PMID: 27592691 Review.
15
High-Intensity Interval Training for Patients With Cardiovascular Disease-Is It Safe? A Systematic Review.
Wewege MA, Ahn D, Yu J, Liou K, Keech A.
J Am Heart Assoc. 2018 Nov 6;7(21):e009305. doi: 10.1161/JAHA.118.009305.
PMID: 30376749 Free PMC article.
16
Exercise-based cardiac rehabilitation and parasympathetic function in patients with coronary artery disease systematic review and meta-analysis.
Manresa-Rocamora A, Ribeiro F, Sarabia JM, .bias J, Oliveira NL, Vera-Garc.a FJ, Moya-Ram.n M.
Clin Auton Res. 2020 Apr 8. doi: 10.1007/s10286-020-00687-0. Online ahead of print.
PMID: 32270406 Review.
Page 3
17
Interventions to support return to work for people with coronary heart disease.
Hegewald J, Wegewitz UE, Euler U, van Dijk JL, Adams J, Fishta A, Heinrich P, Seidler A.
Cochrane Database Syst Rev. 2019 Mar 14;3(3):CD010748. doi: 10.1002/14651858.CD010748.pub2.
PMID: 30869157 Free PMC article.
18
Coronary vasomotion and exercise-induced adaptations in coronary artery disease patients: A systematic meta-analysis.
Ahmadi A, Dabidi Roshan V, Jalali A.
J Res Med Sci. 2020 Aug 24;25d76. doi: 10.4103/jrms.JRMS_580_18. eCollection 2020.
PMID: 33088313 Free PMC article. Review.
19
Physical Activity, All-Cause and Cardiovascular Mortality, and Cardiovascular Disease.
Kraus WE, Powell KE, Haskell WL, Janz KF, Campbell WW, Jakicic JM, Troiano RP, Sprow K, Torres A, Piercy KL; 2018 PHYSICAL ACTIVITY ADVISORY COMMITTEE*.
Med Sci Sports Exerc. 2019 Jun;51(6):1270-1281. doi: 10.1249/MSS.0000000000001939.
PMID: 31095084 Free PMC article.
20
Is exercise-based cardiac rehabilitation effective? A systematic review and meta-analysis to re-examine the Powell R, McGregor G, Ennis S, Kimani PK, Underwood M.
BMJ Open. 2018 Mar 14;8(3):e019656. doi: 10.1136/bmjopen-2017-019656.
PMID: 29540415 Free PMC article. Review.
21 Coronary Artery Disease Patient Perspectives on Exercise Participation.
Campkin LM, Boyd JM, Campbell DJT.
J Cardiopulm Rehabil Prev. 2017 Sep;37(5):305-314. doi: 10.1097/HCR.0000000000000195.
PMID: 28858031 Review.
22
High-intensity interval training versus moderate-intensity continuous training within cardiac rehabilitation: a review and meta-analysis.
Hannan AL, Hing W, Simas V, Climstein M, Coombes JS, Jayasinghe R, Byrnes J, Furness J.
Open Access J Sports Med. 2018 Jan 26;9d1-17. doi: 10.2147/OAJSM.S150596. eCollection 2018.
PMID: 29416382 Free PMC article. Review.
23
Effects of exercise on endothelial progenitor cells in patients with cardiovascular disease: A systematic review meta-analysis of randomized controlled trials.
Cavalcante SL, Lopes S, Bohn L, Cavero-Redondo I, .lvarez-Bueno C, Viamonte S, Santos M, Oliveira J, Ribeiro F.
Rev Port Cardiol. 2019 Nov;38(11):817-827. doi: 10.1016/j.repc.2019.02.016. Epub 2020 Feb 7.
PMID: 32037059 English, Portuguese.
25
Effects of Exercise Therapy for Adults With Coronary Heart Disease: A Systematic Review and Meta-analysis Randomized Controlled Trials.
Chair SY, Zou H, Cao X.
J Cardiovasc Nurs. 2021 Jan/Feb;36(1):56-77. doi: 10.1097/JCN.0000000000000713.
PMID: 32649373
26
Exercise and inflammation in coronary artery disease: A systematic review and meta-analysis of randomised Thompson G, Davison GW, Crawford J, Hughes CM.
J Sports Sci. 2020 Apr;38(7):814-826. doi: 10.1080/02640414.2020.1735684. Epub 2020 Mar 4.
PMID: 32129713
Page 4
27
Exercise-based cardiac rehabilitation for adults with stable angina.
Long L, Anderson L, Dewhirst AM, He J, Bridges C, Gandhi M, Taylor RS.
Cochrane Database Syst Rev. 2018 Feb 2;2(2):CD012786. doi: 10.1002/14651858.CD012786.pub2.
PMID: 29394453 Free PMC article. Review.
29
Comparison of Treadmill and Cycle Ergometer Exercise During Cardiac Rehabilitation: A Meta-analysis.
Gerlach S, Mermier C, Kravitz L, Degnan J, Dalleck L, Zuhl M.
Arch Phys Med Rehabil. 2020 Apr;101(4):690-699. doi: 10.1016/j.apmr.2019.10.184. Epub 2019 Nov 15.
PMID: 31738893
30
Nordic walking for individuals with cardiovascular disease: A systematic review and meta-analysis of randomized controlled trials.
Cugusi L, Manca A, Yeo TJ, Bassareo PP, Mercuro G, Kaski JC.
Eur J Prev Cardiol. 2017 Dec;24(18):1938-1955. doi: 10.1177/2047487317738592. Epub 2017 Oct 25.
PMID: 29067853 Review.
31
Yoga for secondary prevention of coronary heart disease: A systematic review and meta-analysis.
Li J, Gao X, Hao X, Kantas D, Mohamed EA, Zheng X, Xu H, Zhang L.
Complement Ther Med. 2020 Dec 15;57d102643. doi: 10.1016/j.ctim.2020.102643. Online ahead of print.
PMID: 33338581 Free article. Review.
33
Health-related quality of life and exercise-based cardiac rehabilitation in contemporary acute coronary syndrome patients: a systematic review and meta-analysis.
Candelaria D, Randall S, Ladak L, Gallagher R.
Qual Life Res. 2020 Mar;29(3):579-592. doi: 10.1007/s11136-019-02338-y. Epub 2019 Nov 5.
PMID: 31691204
34
The association of resistance training with mortality: A systematic review and meta-analysis.
Saeidifard F, Medina-Inojosa JR, West CP, Olson TP, Somers VK, Bonikowske AR, Prokop LJ, Vinciguerra M, Lopez-Jimenez F.
Eur J Prev Cardiol. 2019 Oct;26(15):1647-1665. doi: 10.1177/2047487319850718. Epub 2019 May 19.
PMID: 31104484
35
The Impact of Text Message On Self-Management for Coronary Heart Disease: A Meta-Analysis of Randomized Controlled Trials.
Wan Y, Wu X, Kou Y.
Heart Surg Forum. 2020 Feb 10;23(1):E018-E024. doi: 10.1532/hsf.2519.
PMID: 32118537
36
Effects of exercise on c-reactive protein in healthy patients and in patients with heart disease: A meta-analysis.
Hammonds TL, Gathright EC, Goldstein CM, Penn MS, Hughes JW.
Heart Lung. 2016 May-Jun;45(3):273-82. doi: 10.1016/j.hrtlng.2016.01.009. Epub 2016 Feb 23.
PMID: 26916454 Free PMC article. Review.
Page 5
38
Aerobic Interval vs. Continuous Training in Patients with Coronary Artery Disease or Heart Failure: An Updated
Systematic Review and Meta-Analysis with a Focus on Secondary Outcomes.
Pattyn N, Beulque R, Cornelissen V.
Sports Med. 2018 May;48(5):1189-1205. doi: 10.1007/s40279-018-0885-5.
PMID: 29502328 Review.
40
Can high-intensity interval training improve physical and mental health outcomes? A meta-review of 33 systematic
reviews across the lifespan.
Martland R, Mondelli V, Gaughran F, Stubbs B.
J Sports Sci. 2020 Feb;38(4):430-469. doi: 10.1080/02640414.2019.1706829. Epub 2019 Dec 31.
PMID: 31889469
41
Cardiac Rehabilitation and Exercise Prescription in Symptomatic Patients with Non-Obstructive Coronary Artery Disease-a Systematic Review.
Kissel CK, Nikoletou D.
Curr Treat Options Cardiovasc Med. 2018 Aug 18;20(9):78. doi: 10.1007/s11936-018-0667-2.
PMID: 30121850 Free PMC article. Review.
42
Effects of physical exercise on the autonomic nervous system in patients with coronary artery disease: a systematic review.
Figueiredo TG, de Souza HCM, Neves VR, do R.go Barros AEV, Dornelas de Andrade AF, Brand.o DC.
Expert Rev Cardiovasc Ther. 2020 Nov;18(11):749-759. doi: 10.1080/14779072.2020.1813568. Epub 2020 Oct 20.
PMID: 32885689
43
The influence of training characteristics on the effect of exercise training in patients with coronary artery disease Systematic review and meta-regression analysis.
Kraal JJ, Vromen T, Spee R, Kemps HMC, Peek N.
Int J Cardiol. 2017 Oct 15;245d52-58. doi: 10.1016/j.ijcard.2017.07.051. Epub 2017 Jul 18.
PMID: 28735757 Review.
44
Does contemporary exercise-based cardiac rehabilitation improve quality of life for people with coronary artery disease? A systematic review and meta-analysis.
McGregor G, Powell R, Kimani P, Underwood M.
BMJ Open. 2020 Jun 7;10(6):e036089. doi: 10.1136/bmjopen-2019-036089.
PMID: 32513887 Free PMC article.
45
Treatment of Anxiety in Patients With Coronary Heart Disease: A Systematic Review.
Farquhar JM, Stonerock GL, Blumenthal JA.
Psychosomatics. 2018 Jul-Aug;59(4):318-332. doi: 10.1016/j.psym.2018.03.008. Epub 2018 Mar 27.
PMID: 29735242 Free PMC article.
Page 6
48
Comparative Effectiveness of the Core Components of Cardiac Rehabilitation on Mortality and Morbidity: A Systematic
Review and Network Meta-Analysis.
Kabboul NN, Tomlinson G, Francis TA, Grace SL, Chaves G, Rac V, Daou-Kabboul T, Bielecki JM, Alter DA, Krahn M.
J Clin Med. 2018 Dec 4;7(12):514. doi: 10.3390/jcm7120514.
PMID: 30518047 Free PMC article. Review.
50
Implementing resistance training in the rehabilitation of coronary heart disease: A systematic review and metaanalysis.
Xanthos PD, Gordon BA, Kingsley MI.
Int J Cardiol. 2017 Mar 1;230d493-508. doi: 10.1016/j.ijcard.2016.12.076. Epub 2016 Dec 23.
PMID: 28040292 Review.
51
Interventions to promote patient utilisation of cardiac rehabilitation.
Santiago de Ara.jo Pio C, Chaves GS, Davies P, Taylor RS, Grace SL.
Cochrane Database Syst Rev. 2019 Feb 1;2(2):CD007131. doi: 10.1002/14651858.CD007131.pub4.
PMID: 30706942 Free PMC article.
52
Longer-term effects of home-based exercise interventions on exercise capacity and physical activity in coronary artery disease patients: A systematic review and meta-analysis.
Claes J, Buys R, Budts W, Smart N, Cornelissen VA.
Eur J Prev Cardiol. 2017 Feb;24(3):244-256. doi: 10.1177/2047487316675823. Epub 2016 Oct 27.
PMID: 27798366 Review.
53
Effects of Tai Chi-based cardiac rehabilitation on aerobic endurance, psychosocial well-being, and cardiovascular reduction among patients with coronary heart disease: A systematic review and meta-analysis.
Liu T, Chan AW, Liu YH, Taylor-Piliae RE.
Eur J Cardiovasc Nurs. 2018 Apr;17(4):368-383. doi: 10.1177/1474515117749592. Epub 2017 Dec 19.
PMID: 29256626
54
Impact of technology-based patient education on modifiable cardiovascular risk factors of people with coronary disease: A systematic review.
Halldorsdottir H, Thoroddsen A, Ingadottir B.
Patient Educ Couns. 2020 Oct;103(10):2018-2028. doi: 10.1016/j.pec.2020.05.027. Epub 2020 Jun 3.
PMID: 32595027 Review.
Page 7
55
Hybrid versus traditional cardiac rehabilitation models: a systematic review and meta-analysis.
Wu C, Li Y, Chen J.
Kardiol Pol. 2018;76(12):1717-1724. doi: 10.5603/KP.a2018.0175. Epub 2018 Sep 25.
PMID: 30251248
57
Exercise Parameters and Outcome Measures Used in Cardiac Rehabilitation Programs Following Median Sternotomy the Elderly: A Systematic Review and Meta-Analysis.
Pengelly J, Pengelly M, Lin KY, Royse C, Karri R, Royse A, Bryant A, Williams G, El-Ansary D.
Heart Lung Circ. 2019 Oct;28(10):1560-1570. doi: 10.1016/j.hlc.2019.05.098. Epub 2019 May 25.
PMID: 31176628
59
The Effect of Tai Chi on Cardiorespiratory Fitness for Coronary Disease Rehabilitation: A Systematic Review Analysis.
Yang YL, Wang YH, Wang SR, Shi PS, Wang C.
Front Physiol. 2018 Jan 4;8d1091. doi: 10.3389/fphys.2017.01091. eCollection 2017.
PMID: 29354065 Free PMC article.
61
The prognostic value of heart rate recovery in patients with coronary artery disease: A systematic review and Lachman S, Terbraak MS, Limpens J, Jorstad H, Lucas C, Scholte Op Reimer W, Boekholdt SM, Ter Riet G, Peters RJG.
Am Heart J. 2018 May;199d163-169. doi: 10.1016/j.ahj.2018.02.008. Epub 2018 Feb 13.
PMID: 29754656
62
Health literacy and coronary artery disease: A systematic review.
Ghisi GLM, Chaves GSDS, Britto RR, Oh P.
Patient Educ Couns. 2018 Feb;101(2):177-184. doi: 10.1016/j.pec.2017.09.002. Epub 2017 Sep 6.
PMID: 28899710
63
The association between physical activity with incident obesity, coronary heart disease, diabetes and hypertension adults: a systematic review of longitudinal studies published after 2012.
Cleven L, Krell-Roesch J, Nigg CR, Woll A.
BMC Public Health. 2020 May 19;20(1):726. doi: 10.1186/s12889-020-08715-4.
PMID: 32429951 Free PMC article.
Page 8
68
Diagnostic accuracy of treadmill exercise tests among Chinese women with coronary artery diseases: A systematic review and meta-analysis.
Sun Y, Li W, Yin L, Wei L, Wang Y.
Int J Cardiol. 2017 Jan 15;227d894-900. doi: 10.1016/j.ijcard.2016.11.129. Epub 2016 Nov 9.
PMID: 27919426 Review.
69
Combined Aerobic and Resistance Training for Peak Oxygen Uptake, Muscle Strength, and Hypertrophy After
Artery Disease: a Systematic Review and Meta-Analysis.
Lee J, Lee R, Stone AJ.
J Cardiovasc Transl Res. 2020 Aug;13(4):601-611. doi: 10.1007/s12265-019-09922-0. Epub 2019 Oct 27.
PMID: 31656988
71
A systematic review of published interventions for primary and secondary prevention of ischaemic heart disease in rural populations of Australia.
Alston LV, Peterson KL, Jacobs JP, Allender S, Nichols M.
BMC Public Health. 2016 Aug 27;16(1):895. doi: 10.1186/s12889-016-3548-1.
PMID: 27567666 Free PMC article. Review.
72
Additional effects of psychological interventions on subjective and objective outcomes compared with exercise cardiac rehabilitation alone in patients with cardiovascular disease: A systematic review and meta-analysis.
Albus C, Herrmann-Lingen C, Jensen K, Hackbusch M, Münch N, Kuncewicz C, Grilli M, Schwaab B, Rauch B; German Society of Cardiovascular
Prevention & Rehabilitation (DGPR).
Eur J Prev Cardiol. 2019 Jul;26(10):1035-1049. doi: 10.1177/2047487319832393. Epub 2019 Mar 11.
PMID: 30857429 Free PMC article.
Page 9
77
Gelatinases and physical exercise: A systematic review of evidence from human studies.
Lo Presti R, Hopps E, Caimi G.
Medicine (Baltimore). 2017 Sep;96(37):e8072. doi: 10.1097/MD.0000000000008072.
PMID: 28906407 Free PMC article. Review.
78
The Contribution of Individual Exercise Training Components to Clinical Outcomes in Randomised Controlled Cardiac Rehabilitation: A Systematic Review and Meta-regression.
Abell B, Glasziou P, Hoffmann T.
Sports Med Open. 2017 Dec;3(1):19. doi: 10.1186/s40798-017-0086-z. Epub 2017 May 5.
PMID: 28477308 Free PMC article. Review.
79
Cardiovascular Health of Retired Field-Based Athletes: A Systematic Review and Meta-analysis.
McHugh C, Hind K, Davey D, Wilson F.
Orthop J Sports Med. 2019 Aug 19;7(8):2325967119862750. doi: 10.1177/2325967119862750. eCollection 2019 Aug.
PMID: 31457065 Free PMC article. Review.
80 Implementation of Telerehabilitation Interventions for the Self-Management of Cardiovascular Disease: Systematic
Review.
Subedi N, Rawstorn JC, Gao L, Koorts H, Maddison R.
JMIR Mhealth Uhealth. 2020 Nov 27;8(11):e17957. doi: 10.2196/17957.
PMID: 33245286 Free PMC article. Review.
83
The Effect of Cardiac Rehabilitation on Health-Related Quality of Life in Patients With Coronary Artery Disease
Meta-analysis.
Francis T, Kabboul N, Rac V, Mitsakakis N, Pechlivanoglou P, Bielecki J, Alter D, Krahn M.
Can J Cardiol. 2019 Mar;35(3):352-364. doi: 10.1016/j.cjca.2018.11.013. Epub 2018 Nov 24.
PMID: 30825955
87
Exaggerated systolic hypertensive response to exercise predicts cardiovascular events: a systematic review Per.uku L, Bajraktari G, Jashari H, Byty.i I, Ibrahimi P, Henein MY.
Pol Arch Intern Med. 2019 Dec 23;129(12):855-863. doi: 10.20452/pamw.15007. Epub 2019 Oct 2.
PMID: 31577264
90
Barriers for Nonparticipation and Dropout of Women in Cardiac Rehabilitation Programs: A Systematic Review.
Resurrecci.n DM, Motrico E, Rigabert A, Rubio-Valera M, Conejo-Cer.n S, Pastor L, Moreno-Peral P.
J Womens Health (Larchmt). 2017 Aug;26(8):849-859. doi: 10.1089/jwh.2016.6249. Epub 2017 Apr 7.
PMID: 28388314 Review.
Page 11
91
Effectiveness of Low to Moderate Physical Exercise Training on the Level of Low-Density Lipoproteins: A Systematic
Review.
Albarrati AM, Alghamdi MSM, Nazer RI, Alkorashy MM, Alshowier N, Gale N.
Biomed Res Int. 2018 Nov 1;2018d5982980. doi: 10.1155/2018/5982980. eCollection 2018.
PMID: 30515408 Free PMC article.
93
Diabetes and Hypertension Consistently Predict the Presence and Extent of Coronary Artery Calcification in
Symptomatic Patients: A Systematic Review and Meta-Analysis.
Nicoll R, Zhao Y, Ibrahimi P, Olivecrona G, Henein M.
Int J Mol Sci. 2016 Sep 6;17(9):1481. doi: 10.3390/ijms17091481.
PMID: 27608015 Free PMC article. Review.
97
[Health benefits of aerobic training programs in adults aged 70 or over: A systematic review].
Bouaziz W, Vogel T, Schmitt E, Kaltenbach G, Geny B, Lang PO.
Presse Med. 2017 Sep;46(9):794-807. doi: 10.1016/j.lpm.2017.05.028. Epub 2017 Jun 28.
PMID: 28668364 Review. French.
98 Dog Ownership and Survival: A Systematic Review and Meta-Analysis.
Kramer CK, Mehmood S, Suen RS.
Circ Cardiovasc Qual Outcomes. 2019 Oct;12(10):e005554. doi: 10.1161/CIRCOUTCOMES.119.005554. Epub 2019 Oct 8.
PMID: 31592726
101
Impact of wearable physical activity monitoring devices with exercise prescription or advice in the maintenance of cardiac rehabilitation: systematic review and meta-analysis.
Hannan AL, Harders MP, Hing W, Climstein M, Coombes JS, Furness J.
BMC Sports Sci Med Rehabil. 2019 Jul 30;11d14. doi: 10.1186/s13102-019-0126-8. eCollection 2019.
PMID: 31384474 Free PMC article.
102
Physical inactivity in Saudi Arabia revisited: A systematic review of inactivity prevalence and perceived barriers living.
Al-Hazzaa HM.
Int J Health Sci (Qassim). 2018 Nov-Dec;12(6):50-64.
PMID: 30534044 Free PMC article. Review.
103
Home-based versus centre-based cardiac rehabilitation: abridged Cochrane systematic review and meta-analysis.
Buckingham SA, Taylor RS, Jolly K, Zawada A, Dean SG, Cowie A, Norton RJ, Dalal HM.
Open Heart. 2016 Sep 14;3(2):e000463. doi: 10.1136/openhrt-2016-000463. eCollection 2016.
PMID: 27738516 Free PMC article.
104
Behaviour change techniques in home-based cardiac rehabilitation: a systematic review.
Heron N, Kee F, Donnelly M, Cardwell C, Tully MA, Cupples ME.
Br J Gen Pract. 2016 Oct;66(651):e747-57. doi: 10.3399/bjgp16X686617. Epub 2016 Aug 1.
PMID: 27481858 Free PMC article. Review.
107
Appropriate Use of Cardiac Stress Testing with Imaging: A Systematic Review and Meta-Analysis.
Ladapo JA, Blecker S, O'Donnell M, Jumkhawala SA, Douglas PS.
PLoS One. 2016 Aug 18;11(8):e0161153. doi: 10.1371/journal.pone.0161153. eCollection 2016.
PMID: 27536775 Free PMC article. Review.
109
Impact of implementation intentions on physical activity practice in adults: A systematic review and meta-analysis randomized clinical trials.
Silva MAVD, S.o-Jo.o TM, Brizon VC, Franco DH, Mialhe FL.
PLoS One. 2018 Nov 14;13(11):e0206294. doi: 10.1371/journal.pone.0206294. eCollection 2018.
PMID: 30427874 Free PMC article.
METHOD
The National Library of Medicine www.nlm.govwas searched for ‘Systematic Review’, in the last 5 years. 20 reviews were identified.
These were reviewed by Muir Gray for relevance eg some systematic reviews were focused on drug therapy, this removed 7 reviews from the database and the remaining 13 are listed below.
USING THE DATABASE
To read the abstract or the full text simple copy the doi, for example
doi: 10.1016/j.bjpt.2017.06.004. and paste it into your web browser
1
Exercise-based cardiac rehabilitation for adults with atrial fibrillation.
Risom SS, Zwisler AD, Johansen PP, Sibilitz KL, Lindschou J, Gluud C, Taylor RS, Svendsen JH, Berg SK.
Cochrane Database Syst Rev. 2017 Feb 9;2(2):CD011197. doi: 10.1002/14651858.CD011197.pub2.
PMID: 28181684 Free PMC article. Review.
3
Lifestyle Therapy for the Management of Atrial Fibrillation.
Abdul-Aziz AA, Altawil M, Lyon A, MacEachern M, Richardson CR, Rubenfire M, Pelosi F Jr, Jackson EA.
Am J Cardiol. 2018 May 1;121(9):1112-1117. doi: 10.1016/j.amjcard.2018.01.023. Epub 2018 Feb 7.
PMID: 29650239
4
Efficacy of Physical Exercise on the Quality of Life, Exercise Ability, and Cardiopulmonary Fitness of Patients Atrial Fibrillation: A Systematic Review and Meta-Analysis.
Shi S, Shi J, Jia Q, Shi S, Yuan G, Hu Y.
Front Physiol. 2020 Jul 24;11c740. doi: 10.3389/fphys.2020.00740. eCollection 2020.
PMID: 32792965 Free PMC article.
5
Meta-Analysis of Atrial Fibrillation Ablation in Patients with Systolic Heart Failure.
Ruzieh M, Foy AJ, Aboujamous NM, Moroi MK, Naccarelli GV, Ghahramani M, Kanjwal S, Marine JE, Kanjwal K.
Cardiovasc Ther. 2019 Jan 6;2019c8181657. doi: 10.1155/2019/8181657. eCollection 2019.
PMID: 31772616 Free PMC article.
7
Exercise-based cardiac rehabilitation improves exercise capacity and health-related quality of life in people fibrillation: a systematic review and meta-analysis of randomised and non-randomised trials.
Smart NA, King N, Lambert JD, Pearson MJ, Campbell JL, Risom SS, Taylor RS.
Open Heart. 2018 Dec 20;5(2):e000880. doi: 10.1136/openhrt-2018-000880. eCollection 2018.
PMID: 30613410 Free PMC article.
8
Evidence-based prevention of Alzheimer's disease: systematic review and meta-analysis of 243 observational prospective studies and 153 randomised controlled trials.
Yu JT, Xu W, Tan CC, Andrieu S, Suckling J, Evangelou E, Pan A, Zhang C, Jia J, Feng L, Kua EH, Wang YJ, Wang HF, Tan MS, Li JQ, Hou XH, Mok V, Tan L, Dong Q, Touchon J, Gauthier S, Aisen PS, Vellas B.
J Neurol Neurosurg Psychiatry. 2020 Nov;91(11):1201-1209. doi: 10.1136/jnnp-2019-321913. Epub 2020 Jul 20.
PMID: 32690803 Free PMC article. Review.
9
Physical activity volume in relation to risk of atrial fibrillation. A non-linear meta-regression analysis.
Ricci C, Gervasi F, Gaeta M, Smuts CM, Schutte AE, Leitzmann MF.
Eur J Prev Cardiol. 2018 May;25(8):857-866. doi: 10.1177/2047487318768026. Epub 2018 Mar 29.
PMID: 29591534
10
Atrial fibrillation in athletes and general population: A systematic review and meta-analysis.
Li X, Cui S, Xuan D, Xuan C, Xu D.
Medicine (Baltimore). 2018 Dec;97(49):e13405. doi: 10.1097/MD.0000000000013405.
PMID: 30544416 Free PMC article.
11
Self-reported physical activity and atrial fibrillation risk: A systematic review and meta-analysis.
Mishima RS, Verdicchio CV, Noubiap JJ, Ariyaratnam JP, Gallagher C, Jones D, Malik V, Agbaedeng TA, Middeldorp ME, Lau DH, Sanders Heart Rhythm. 2020 Dec 19cS1547-5271(20)31165-6. doi: 10.1016/j.hrthm.2020.12.017. Online ahead of print.
PMID: 33348059
13
Exercise-based cardiac rehabilitation for adult patients with an implantable cardioverter defibrillator.
Nielsen KM, Zwisler AD, Taylor RS, Svendsen JH, Lindschou J, Anderson L, Jakobsen JC, Berg SK.
Cochrane Database Syst Rev. 2019 Feb 12;2(2):CD011828. doi: 10.1002/14651858.CD011828.pub2.
PMID: 30746679 Free PMC article.
15
The Effects of Cardiac Rehabilitation in Patients With Atrial Fibrillation: A Systematic Review.
Reed JL, Terada T, Chirico D, Prince SA, Pipe AL.
Can J Cardiol. 2018 Oct;34(10 Suppl 2):S284-S295. doi: 10.1016/j.cjca.2018.07.014. Epub 2018 Jul 23.
PMID: 30274639
16
Catheter ablation versus medical rate control for persistent atrial fibrillation in patients with heart failure: A systematic review and meta-analysis of randomized controlled trials.
Zhu M, Zhou X, Cai H, Wang Z, Xu H, Chen S, Chen J, Xu X, Xu H, Mao W.
Medicine (Baltimore). 2016 Jul;95(30):e4377. doi: 10.1097/MD.0000000000004377.
PMID: 27472728 Free PMC article. Review.
19
Data management and wearables in older adults: A systematic review.
Alharbi M, Straiton N, Smith S, Neubeck L, Gallagher R.
Maturitas. 2019 Jun;124c100-110. doi: 10.1016/j.maturitas.2019.03.012. Epub 2019 Mar 18.
PMID: 30910279
Exercise therapy for people with Heart Failure
METHOD
The National Library of Medicine www.nlm.govwas searched for ‘Systematic Review’, in the last 5 years. 176 reviews were identified.
These were reviewed by Muir Gray for relevance eg some systematic reviews were focused on drug therapy, this removed 81 reviews from the database and the remaining 95 are listed below.
USING THE DATABASE
To read the abstract or the full text simple copy the doi, for example
doi: 10.1016/j.bjpt.2017.06.004. and paste it into your web browser
1
Exercise-based cardiac rehabilitation for adults with heart failure.
Long L, Mordi IR, Bridges C, Sagar VA, Davies EJ, Coats AJ, Dalal H, Rees K, Singh SJ, Taylor RS.
Cochrane Database Syst Rev. 2019 Jan 29;1(1):CD003331. doi: 10.1002/14651858.CD003331.pub5.
PMID: 30695817 Free PMC article.
BACKGROUND: Chronic heart failure (HF) is a growing global health challenge. People with HF
experience substantial burden that includes low exercise tolerance, poor health-related quality of
life (HRQoL), increased risk of mortality and hospital admission, an …
2
Chronic Heart Failure and Exercise Rehabilitation: A Systematic Review and Meta-Analysis.
Palmer K, Bowles KA, Paton M, Jepson M, Lane R.
Arch Phys Med Rehabil. 2018 Dec;99(12):2570-2582. doi: 10.1016/j.apmr.2018.03.015. Epub 2018
Apr 24.
PMID: 29698639
OBJECTIVE: The aim of this systematic review was to identify the effect of specific exercise
parameters on physical function and quality of life (QOL) in people with chronic heart failure living in the community. ...Current evidence suggests that engagement w …
3
Comparing exercise training modalities in heart failure: A systematic review
and meta-analysis.
Cornelis J, Beckers P, Taeymans J, Vrints C, Vissers D.
Int J Cardiol. 2016 Oct 15;221e867-76. doi: 10.1016/j.ijcard.2016.07.105. Epub 2016 Jul 9.
PMID: 27434363 Review.
Exercise training (ET) is suggested to improve exercise capacity, prognosis, quality of life (QOL)
and functional modifications of the heart in patients with heart failure (HF). ...The primary outcome data were peak oxygen uptake, ventilation ov …
4
High intensity interval training versus moderate intensity continuous training on
exercise capacity and quality of life in patients with heart failure with reduced
ejection fraction: A systematic review and meta-analysis.
Gomes Neto M, Dur.es AR, Concei..o LSR, Saquetto MB, Ellingsen ., Carvalho VO.
Int J Cardiol. 2018 Jun 15;261e134-141. doi: 10.1016/j.ijcard.2018.02.076. Epub 2018 Mar 5.
PMID: 29572084 Review.
OBJECTIVE: The aim of this study was to investigate the effects of high intensity interval training
(HIIT) versus moderate intensity continuous training (MICT) in heart failure patients with reduced
ejection fraction (HFrEF). BACKGROUND: Despite the well-known posit …
5
Exercise-Based Rehabilitation for Heart Failure: Cochrane Systematic Review,
Meta-Analysis, and Trial Sequential Analysis.
Taylor RS, Long L, Mordi IR, Madsen MT, Davies EJ, Dalal H, Rees K, Singh SJ, Gluud C, Zwisler AD.
JACC Heart Fail. 2019 Aug;7(8):691-705. doi: 10.1016/j.jchf.2019.04.023. Epub 2019 Jul 10.
PMID: 31302050 Free article.
OBJECTIVES: This study performed a contemporary systematic review and meta-analysis of
exercise-based cardiac rehabilitation (ExCR) for heart failure (HF). ...Randomized trials comparing
patients undergoing ExCR to control patients not undergoing exercise …
6
Exercise therapy and autonomic function in heart failure patients: a
systematic review and meta-analysis.
Pearson MJ, Smart NA.
Heart Fail Rev. 2018 Jan;23(1):91-108. doi: 10.1007/s10741-017-9662-z.
PMID: 29185161
The aim of this systematic review and meta-analysis was to investigate the effects of exercise
training on parameters of autonomic function in patients with heart failure and where possible
quantify the size of the effect. We conducted database searches (PubM …
7
Effects of exercise training in heart failure with preserved ejection fraction: an
updated systematic literature review.
Leggio M, Fusco A, Loreti C, Limongelli G, Bendini MG, Mazza A, Coraci D, Padua L.
Heart Fail Rev. 2020 Sep;25(5):703-711. doi: 10.1007/s10741-019-09841-x.
PMID: 31399956 Review.
Physical activity is associated with a lower risk of adverse cardiovascular outcomes, including heart failure (HF). Exercise training is a class IA level recommendation in patients with stable HF, but its impact is less clear in heart failure wi …
10
Ivabradine Improves Cardiac Function and Increases Exercise Capacity in
Patients with Chronic Heart Failure.
Pei H, Miao W, Xie WZ, Wang W, Zhao D, Su GH, Zhao Z.
Int Heart J. 2019 Jul 27;60(4):899-909. doi: 10.1536/ihj.18-559. Epub 2019 Jul 12.
PMID: 31308326 Free article.
Additionally, the RRs of heart failure and hospitalization also decreased (RR = 0.91, 95% CI: 0.85-
-0.97, P = 0.006; RR = 0.86, 95% CI: 0.79--0.93, P = 0.0002). ...Adding ivabradine to the standard
anti-heart failure treatment reduced the mortality and …
12
Effect of exercise on diastolic function in heart failure patients: a systematic
review and meta-analysis.
Pearson MJ, Mungovan SF, Smart NA.
Heart Fail Rev. 2017 Mar;22(2):229-242. doi: 10.1007/s10741-017-9600-0.
PMID: 28229273 Review.
The aim of this meta-analysis was to quantify the effect of exercise training on diastolic function in patients with heart failure. Exercise training studies that investigate different indices of diastolic function in patients with heart fail …
13
Exercise-based cardiac rehabilitation in patients with reduced left ventricular
ejection fraction: The Cardiac Rehabilitation Outcome Study in Heart Failure
(CROS-HF): A systematic review and meta-analysis.
Bjarnason-Wehrens B, Nebel R, Jensen K, Hackbusch M, Grilli M, Gielen S, Schwaab B, Rauch B;
German Society of Cardiovascular Prevention and Rehabilitation (DGPR).
Eur J Prev Cardiol. 2020 Jun;27(9):929-952. doi: 10.1177/2047487319854140. Epub 2019 Jun 8.
PMID: 31177833 Free PMC article.
BACKGROUND: In heart failure with reduced left ventricular ejection fraction (HFrEF) patients the
effects of exercise-based cardiac rehabilitation on top of state-of-the-art pharmacological and
device therapy on mortality, hospitalization, exercise …
15
Different exercise therapies for treating heart failure: A protocol for overview
of systematic reviews and network meta-analysis.
Zhang L, Zhao XP, Qiao LJ, Wei WX, Wei M, Ding J, Li YD.
Medicine (Baltimore). 2020 Oct 16;99(42):e22710. doi: 10.1097/MD.0000000000022710.
PMID: 33080723 Free PMC article.
BACKGROUND: Exercise therapies has been shown to be safe and effective as a nonpharmacological management for treating heart failure, At the same time, many clinical trials,
systematic review, and meta-analyses have demonstrated the advantages of exercise …
16
Exercise-based cardiac rehabilitation in heart transplant recipients.
Anderson L, Nguyen TT, Dall CH, Burgess L, Bridges C, Taylor RS.
Cochrane Database Syst Rev. 2017 Apr 4;4(4):CD012264. doi: 10.1002/14651858.CD012264.pub2.
PMID: 28375548 Free PMC article. Review.
BACKGROUND: Heart transplantation is considered to be the gold standard treatment for selected patients with end-stage heart disease when medical therapy has been unable to halt progression of the underlying pathology. ...AUTHORS' CONCLUSIONS: We found modera …
17
[The exercise training restores the heart rate variability in heart failure
patients. A systematic review].
Segovia V, Manterola C, Gonz.lez M, Rodr.guez-N..ez I.
Arch Cardiol Mex. 2017 Oct-Dec;87(4):326-335. doi: 10.1016/j.acmx.2016.12.002. Epub 2017 Jan 5.
PMID: 28065709 Review. Spanish.
In this sense, the autonomic imbalance is the cornerstone of the pathophysiology underlying the
development of these diseases. The aim of this study was to determine the efficacy of exercise
training on heart rate variability (HRV) in adult patients with chronic …
18
Determinants of exercise intolerance in heart failure with preserved ejection
fraction: A systematic review and meta-analysis.
Montero D, Diaz-Ca.estro C.
Int J Cardiol. 2018 Mar 1;254e224-229. doi: 10.1016/j.ijcard.2017.10.114. Epub 2018 Jan 28.
PMID: 29407095 Review.
BACKGROUND: Severe exercise intolerance (EI), demonstrated by impaired peak oxygen
consumption, intrinsically characterizes heart failure with preserved ejection fraction (HFpEF). ...In subgroup analyses, a-vO(2diffpeak) was reduced in HFpEF versus healthy in …
19
Effect of Aerobic Exercise on Peak Oxygen Consumption, VE/VCO(2) Slope,
and Health-Related Quality of Life in Patients with Heart Failure with Preserved
Left Ventricular Ejection Fraction: a Systematic Review and Meta-Analysis.
Gomes-Neto M, Dur.es AR, Concei..o LSR, Roever L, Liu T, Tse G, Biondi-Zoccai G, Goes ALB,
Alves IGN, Ellingsen ., Carvalho VO.
Curr Atheroscler Rep. 2019 Nov 9;21(11):45. doi: 10.1007/s11883-019-0806-6.
PMID: 31707525
PURPOSE OF REVIEW: The aim of this study was to determine the effects of aerobic exercise on
peak oxygen uptake (peak VO(2)), minute ventilation/carbon dioxide production (VE/VCO(2) slope), and health-related quality of life (HRQoL) among patients with heart fail …
20
Home-based versus centre-based cardiac rehabilitation.
Anderson L, Sharp GA, Norton RJ, Dalal H, Dean SG, Jolly K, Cowie A, Zawada A, Taylor RS.
Cochrane Database Syst Rev. 2017 Jun 30;6(6):CD007130. doi: 10.1002/14651858.CD007130.pub4.
PMID: 28665511 Free PMC article. Review.
OBJECTIVES: To compare the effect of home-based and supervised centre-based cardiac
rehabilitation on mortality and morbidity, exercise-capacity, health-related quality of life, and
modifiable cardiac risk factors in patients with heart disease. ...AUTHORS' CONCLUSI …
21
A systematic review of heart failure dyadic self-care interventions focusing on
intervention components, contexts, and outcomes.
Buck HG, Stromberg A, Chung ML, Donovan KA, Harkness K, Howard AM, Kato N, Polo R,
Evangelista LS.
Int J Nurs Stud. 2018 Jan;77e232-242. doi: 10.1016/j.ijnurstu.2017.10.007. Epub 2017 Oct 19.
PMID: 29128777 Free PMC article. Review.
BACKGROUND: Having support from an informal carer is important for heart failure patients. Carers
have the potential to improve patient self-care. At the same time, it should be acknowledged that
caregiving could affect the carer negatively and cause emotional react …
22
Meta-Analysis of the Effects of Cardiac Rehabilitation on Exercise Tolerance
and Cardiac Function in Heart Failure Patients Undergoing Cardiac
Resynchronization Therapy.
Chen ZB, Fan LB, Liu YJ, Zheng YR.
Biomed Res Int. 2019 Nov 28;2019e3202838. doi: 10.1155/2019/3202838. eCollection 2019.
PMID: 31871936 Free PMC article.
OBJECTIVE: To evaluate the effects of cardiac rehabilitation on exercise tolerance and cardiac
function in heart failure patients undergoing cardiac resynchronization therapy (CRT). ...There
were still significant differences in the WMD and 95% CI. CON …
23
Exercise training to reduce sympathetic nerve activity in heart failure patients.
A systematic review and meta-analysis.
Saavedra MJ, Romero F, Roa J, Rodr.guez-N..ez I.
Braz J Phys Ther. 2018 Mar-Apr;22(2):97-104. doi: 10.1016/j.bjpt.2017.06.014. Epub 2017 Jul 7.
PMID: 28733092 Free PMC article. Review.
OBJECTIVE: To determine the effects of exercise training on sympathetic nerve activity in heart
failure patients. ...Clinical trials and quasi-experimental studies were considered for primary article selection. The studies should include patients diagnosed wi …
24
Home-based cardiac rehabilitation for people with heart failure: A systematic
review and meta-analysis.
Zwisler AD, Norton RJ, Dean SG, Dalal H, Tang LH, Wingham J, Taylor RS.
Int J Cardiol. 2016 Oct 15;221e963-9. doi: 10.1016/j.ijcard.2016.06.207. Epub 2016 Jun 28.
PMID: 27441476 Review.
AIMS: To assess the effectiveness of home-based cardiac rehabilitation (CR) for heart failure
compared to either usual medical care (i.e. no CR) or centre-based CR on mortality, morbidity,
exercise capacity, health-related quality of life, drop out, adherence …
25
A systematic review of recent cardiac rehabilitation meta-analyses in patients
with coronary heart disease or heart failure.
Oldridge N, Pakosh M, Grace SL.
Future Cardiol. 2019 May;15(3):227-249. doi: 10.2217/fca-2018-0085. Epub 2019 Jun 4.
PMID: 31161796
Aim: The aim of the project was to conduct a systematic review of meta-analyses of supervised,
home-based or telemedicine-based exercise cardiac rehabilitation (CR) published between July
2011 and April 2018. Materials & methods: Evidence on mortality, hospitalization, …
26
Effect of exercise training on endothelial function in heart failure patients: A
systematic review meta-analysis.
Pearson MJ, Smart NA.
Int J Cardiol. 2017 Mar 15;231e234-243. doi: 10.1016/j.ijcard.2016.12.145. Epub 2016 Dec 28.
PMID: 28089145 Review.
Flow-mediated dilation (FMD) is widely utilised to assess endothelial function and is improved with exercise training in heart failure patients. The aim of this meta-analysis is to quantify the effect of exercise training in patients with heart …
27
The effects of resistance training on muscle strength, quality of life and aerobic
capacity in patients with chronic heart failure - A meta-analysis.
Giuliano C, Karahalios A, Neil C, Allen J, Levinger I.
Int J Cardiol. 2017 Jan 15;227e413-423. doi: 10.1016/j.ijcard.2016.11.023. Epub 2016 Nov 7.
PMID: 27843045 Review.
BACKGROUND: Resistance training (RT) has been utilised to target muscle dysfunction associated with Chronic Heart Failure (CHF). However, there is limited meta-analysis evidence to support its use as a standalone therapy. ...METHODS: We searched Medline, EMBA …
28
Effects of exercise training on anabolic and catabolic markers in patients with
chronic heart failure: a systematic review.
Lee CT, Chen LW, Chien MY.
Heart Fail Rev. 2017 Nov;22(6):723-730. doi: 10.1007/s10741-017-9639-y.
PMID: 28695463 Review.
Decreased anabolism because of alterations in the insulin-like growth factor 1 (IGF-1)/growth
hormone (GH) axis and increased catabolism induced by proinflammatory cytokines like tumor
necrosis factor alpha (TNF-alpha) and interleukin 6 (IL-6) have been reported to contribute to …
29
Targeting the DPP-4-GLP-1 pathway improves exercise tolerance in heart
failure patients: a systematic review and meta-analysis.
Chen C, Huang Y, Zeng Y, Lu X, Dong G.
BMC Cardiovasc Disord. 2019 Dec 23;19(1):311. doi: 10.1186/s12872-019-01275-5.
PMID: 31870322 Free PMC article.
BACKGROUND: The most significant manifestation of heart failure is exercise intolerance. This
systematic review and meta-analysis was performed to investigate whether dipeptidyl peptidase-4
(DPP-4) inhibitors or glucagon-like peptide 1 receptor agonists (GLP- …
30
Effects of combined aerobic and resistance training in patients with heart
failure: A meta-analysis of randomized, controlled trials.
Wang Z, Peng X, Li K, Wu CJ.
Nurs Health Sci. 2019 Jun;21(2):148-156. doi: 10.1111/nhs.12593. Epub 2019 Jan 28.
PMID: 30693617
Cardiac rehabilitation programs consisting of core features of exercise training for patients with
heart failure have demonstrated a wide range of physical and psychological benefits. ...The results demonstrated that combined aerobic and resistance training i …
31
Efficacy and Safety of Exercise Rehabilitation for Heart Failure Patients With
Cardiac Resynchronization Therapy: A Systematic Review and Meta-Analysis.
Ye LF, Wang SM, Wang LH.
Front Physiol. 2020 Aug 21;11e980. doi: 10.3389/fphys.2020.00980. eCollection 2020.
PMID: 32973547 Free PMC article.
Background: Many heart failure (HF) patients admitted to cardiac rehabilitation (CR) centers have a cardiac resynchronization therapy (CRT) device. ...Due to differences in health-related quality of life (HRQOL) assessment methods, we only pooled data that re …
32
Effects of inspiratory muscle training in chronic heart failure patients: A
systematic review and meta-analysis.
Wu J, Kuang L, Fu L.
Congenit Heart Dis. 2018 Mar;13(2):194-202. doi: 10.1111/chd.12586. Epub 2018 Feb 8.
PMID: 29423938 Review.
OBJECTIVE: The aim of this study was to evaluate the effects of inspiratory muscle training (IMT) in chronic heart failure (CHF) patients. DESIGN: We searched MEDLINE, EMBASE, Cochrane Library,
CINHAL, and CBMdisc to collect controlled trials on the application of i …
34
Respiratory training interventions improve health status of heart failure
patients: A systematic review and network meta-analysis of randomized
controlled trials.
Wang MH, Yeh ML.
World J Clin Cases. 2019 Sep 26;7(18):2760-2775. doi: 10.12998/wjcc.v7.i18.2760.
PMID: 31616691 Free PMC article.
BACKGROUND: Prior studies indicate that doing breathing exercises improves physical
performance and quality of life (QoL) in heart failure patients. ...CONCLUSION: This study supports that high- and medium-intensity machine-assisted training improves exerc …
35
Combined Exercise and Inspiratory Muscle Training in Patients With Heart
Failure: A SYSTEMATIC REVIEW AND META-ANALYSIS.
Neto MG, Martinez BP, Concei..o CS, Silva PE, Carvalho VO.
J Cardiopulm Rehabil Prev. 2016 Nov/Dec;36(6):395-401. doi: 10.1097/HCR.0000000000000184.
PMID: 27182763 Review.
PURPOSE: Studies have reported the benefits of exercise and inspiratory muscle training (IMT) in
patients with heart failure (HF); however, there is no meta-analysis on the effects of the
combination of exercise and IMT in patients with HF. ...Weighted …
36
The effects of exercise on VO(2)peak, quality of life and hospitalization in heart
failure patients: A systematic review with meta-analyses.
Dallas K, Dinas PC, Chryssanthopoulos C, Dallas G, Maridaki M, Koutsilieris M, Philippou A.
Eur J Sport Sci. 2020 Nov 29e1-14. doi: 10.1080/17461391.2020.1846081. Online ahead of print.
PMID: 33138729
Hospitalization incidence of heart failure patients was also lower in the exercise compared to
control group (fixed-effect Odds Ratio: 0.56, 95% CI: 0.42-0.75, p < 0.0001; 26 trials, 4,664
participants). Exercise-based rehabilitation improves V0(2)
39
Cost-effectiveness of exercise therapy in patients with coronary heart
disease, chronic heart failure and associated risk factors: A systematic review
of economic evaluations of randomized clinical trials.
Oldridge N, Taylor RS.
Eur J Prev Cardiol. 2020 Jul;27(10):1045-1055. doi: 10.1177/2047487319881839. Epub 2019 Oct 26.
PMID: 31657233
AIMS: Prescribed exercise is effective in adults with coronary heart disease (CHD), chronic heart
failure (CHF), intermittent claudication, body mass index (BMI) 25 kg/m(2), hypertension or type 2 diabetes mellitus (T2DM), but the evidence for its cost …
42
The effect of resistance training on clinical outcomes in heart failure: A
systematic review and meta-analysis.
Jewiss D, Ostman C, Smart NA.
Int J Cardiol. 2016 Oct 15;221e674-81. doi: 10.1016/j.ijcard.2016.07.046. Epub 2016 Jul 5.
PMID: 27423089 Review.
OBJECTIVES: To quantify the change in effect sizes, for selected clinical outcome measures, in
people with heart failure, from resistance exercise, either in isolation, or in combination with
aerobic training. BACKGROUND: Most exercise training data in …
43
The Effect of Exercise Training Intensity on Quality of Life in Heart Failure
Patients: A Systematic Review and Meta-Analysis.
Ostman C, Jewiss D, Smart NA.
Cardiology. 2017;136(2):79-89. doi: 10.1159/000448088. Epub 2016 Aug 27.
PMID: 27577715 Review.
OBJECTIVES: To establish if exercise training intensity produces different effect sizes for quality of life in heart failure. ...METHODS: We conducted a MEDLINE search (1985 to February 2016) for exercise-based rehabilitation trials in heart …
44
High-intensity Interval Training Dosage for Heart Failure and Coronary Artery
Disease Cardiac Rehabilitation. A Systematic Review and Meta-analysis.
Ballesta Garc.a I, Rubio Arias J., Ramos Campo DJ, Mart.nez Gonz.lez-Moro I, Carrasco Poyatos M. Rev Esp Cardiol (Engl Ed). 2019 Mar;72(3):233-243. doi: 10.1016/j.rec.2018.02.015. Epub 2018 Apr
9.
PMID: 29650445 English, Spanish.
The objective of this study was to identify the most effective doses of HIT to optimize peak VO(2) in coronary artery disease (CAD) and heart failure (HF) patients. METHODS: A search was conducted in 6 databases (MEDLINE, Web of Science, LILACS, CINAHL, Academic Sea …
46
Benefits of Tai Chi Exercise Among Adults With Chronic Heart Failure: A
Systematic Review and Meta-Analysis.
Taylor-Piliae R, Finley BA.
J Cardiovasc Nurs. 2020 Sep/Oct;35(5):423-434. doi: 10.1097/JCN.0000000000000703.
PMID: 32544110
BACKGROUND: Exercise-based cardiac rehabilitation is safe and effective for adults with chronic
heart failure (CHF), yet services are greatly underutilized. However, tai chi is a popular and safe
form of exercise among older adults with chronic health …
47
Influence of exercise on oxidative stress in patients with heart failure.
Sties SW, Andreato LV, de Carvalho T, Gonz.les AI, Angarten VG, Ulbrich AZ, de Mara LS, Netto AS,
da Silva EL, Andrade A.
Heart Fail Rev. 2018 Mar;23(2):225-235. doi: 10.1007/s10741-018-9686-z.
PMID: 29497889
Reactive oxygen species play an important role in the pathophysiology of heart failure (HF). In
contrast, regular physical exercise can promote adaptations to reactive oxygen species that are
beneficial for patients with HF. We completed a systematic review o …
48
Acupuncture for heart failure: A systematic review of clinical studies.
Lee H, Kim TH, Leem J.
Int J Cardiol. 2016 Nov 1;222e321-331. doi: 10.1016/j.ijcard.2016.07.195. Epub 2016 Jul 30.
PMID: 27500758 Review.
Another study reported an improved left ventricular ejection fraction by 9.95% (95% CI 3.24, 16.66).
In five chronic heart failure studies, acupuncture improved exercise capacity, quality of life,
hemodynamic parameters, and time domain heart rate vari …
49
Frailty Assessment in Heart Failure: an Overview of the Multi-domain
Approach.
McDonagh J, Ferguson C, Newton PJ.
Curr Heart Fail Rep. 2018 Feb;15(1):17-23. doi: 10.1007/s11897-018-0373-0.
PMID: 29353333
PURPOSE OF REVIEW: The study aims (1) to provide a contemporary description of frailty
assessment in heart failure and (2) to provide an overview of multi-domain frailty assessment in
heart failure. RECENT FINDINGS: Frailty assessment is an important p …
51
High-Intensity Interval Training for Patients With Cardiovascular Disease-Is It
Safe? A Systematic Review.
Wewege MA, Ahn D, Yu J, Liou K, Keech A.
J Am Heart Assoc. 2018 Nov 6;7(21):e009305. doi: 10.1161/JAHA.118.009305.
PMID: 30376749 Free PMC article.
Methods and Results We included trials comparing HIIT with either MICT or usual care in patients with coronary artery disease or heart failure participating in tertiary care services, such as phase 2 (outpatient) CR . ...Conclusions HIIT has shown a relatively low r …
53
Validation of Exercise Capacity as a Surrogate Endpoint in Exercise-Based
Rehabilitation for Heart Failure: A Meta-Analysis of Randomized Controlled
Trials.
Ciani O, Piepoli M, Smart N, Uddin J, Walker S, Warren FC, Zwisler AD, Davos CH, Taylor RS.
JACC Heart Fail. 2018 Jul;6(7):596-604. doi: 10.1016/j.jchf.2018.03.017.
PMID: 29957192
BACKGROUND: EC is often used as a primary outcome in exercise-based cardiac rehabilitation (CR)
trials of heart failure (HF) via direct cardiorespiratory assessment of maximum oxygen uptake
(Vo(2)peak) or through submaximal tests, such as the 6-min walk test …
54
Resistance exercise enhances oxygen uptake without worsening cardiac
function in patients with systolic heart failure: a systematic review and metaanalysis.
Santos FV, Chiappa GR, Ramalho SHR, de Lima ACGB, de Souza FSJ, Cahalin LP, Durigan JLQ, de
Castro I, Cipriano G Jr.
Heart Fail Rev. 2018 Jan;23(1):73-89. doi: 10.1007/s10741-017-9658-8.
PMID: 29199385
Recent literature suggests that resistance training (RT) improves peak oxygen uptake ([Formula: see text] peak), similarly to aerobic exercise (AE) in patients with heart failure (HF), but its effect on cardiac remodeling is controversial. Thus, we examined t …
55
Is Swimming Safe in Heart Failure? A Systematic Review.
Shah P, Pellicori P, Macnamara A, Urbinati A, Clark AL.
Cardiol Rev. 2017 Nov/Dec;25(6):321-325. doi: 10.1097/CRD.0000000000000154.
PMID: 28767502 Review.
It is not clear whether swimming is safe in patients with chronic heart failure. Ten studies examining the hemodynamic effects of acute water immersion (WI) (155 patients; average age 60 years; 86% male; mean left ventricular ejection fraction (LVEF) 29%) and 6 rand …
56
High-intensity interval training for heart failure with preserved ejection fraction:
A protocol for systematic review and meta-analysis.
Zhang S, Zhang J, Liang C, Li X, Meng X.
Medicine (Baltimore). 2020 Jul 2;99(27):e21062. doi: 10.1097/MD.0000000000021062.
PMID: 32629734 Free PMC article.
BACKGROUND: The benefits of high-intensity interval training (HIIT) are well-known, there is
insufficient evidence about the effects of HIIT on heart failure with preserved ejection fraction
(HFpEF). METHOD: Multiple databases include MEDLINE, PubMed, EMBASE, CINAHL …
57
Effect of aerobic and resistance training on inflammatory markers in heart
failure patients: systematic review and meta-analysis.
Pearson MJ, Mungovan SF, Smart NA.
Heart Fail Rev. 2018 Mar;23(2):209-223. doi: 10.1007/s10741-018-9677-0.
PMID: 29392623
Elevated levels of pro-inflammatory markers are evident in patients with heart failure and are
associated with disease severity and prognosis. ...The aim of the systematic review and metaanalysis was to investigate the effect of aerobic (AT) and resistance training …
58
Reported methods for handling missing change standard deviations in metaanalyses
of exercise therapy interventions in patients with heart failure: A
systematic review.
Pearson MJ, Smart NA.
PLoS One. 2018 Oct 18;13(10):e0205952. doi: 10.1371/journal.pone.0205952. eCollection 2018.
PMID: 30335861 Free PMC article.
The aim of this review was to investigate the methods reported and utilised for handling missing
change SDs in meta-analyses, using the topic of exercise therapy in heart failure patients as a
model. METHODS: A systematic search of PubMed, EMBASE and C …
59
Quantifying the Association Between Physical Activity and Cardiovascular
61
Home-Based Cardiac Rehabilitation Alone and Hybrid With Center-Based
Cardiac Rehabilitation in Heart Failure: A Systematic Review and Meta-
Cite Analysis. for Biotechnology Information Log inAnalysis.
Imran HM, Baig M, Erqou S, Taveira TH, Shah NR, Morrison A, Choudhary G, Wu WC.
J Am Heart Assoc. 2019 Aug 20;8(16):e012779. doi: 10.1161/JAHA.119.012779. Epub 2019 Aug 17.
PMID: 31423874 Free PMC article.
Background Center-based cardiac rehabilitation (CBCR) has been shown to improve outcomes in
patients with heart failure (HF). Home-based cardiac rehabilitation (HBCR) can be an alternative to increase access for patients who cannot participate in CBCR. ...
62
Mind-Body Interventions for Individuals With Heart Failure: A Systematic
Review of Randomized Trials.
Gok Metin Z, Ejem D, Dionne-Odom JN, Turkman Y, Salvador C, Pamboukian S, Bakitas M.
J Card Fail. 2018 Mar;24(3):186-201. doi: 10.1016/j.cardfail.2017.09.008. Epub 2017 Sep 20.
PMID: 28939458
BACKGROUND: The effects of mind-body interventions (MBIs) (eg, Tai Chi, yoga, meditation) for
individuals with heart failure (HF) have not been systematically evaluated. METHODS AND
RESULTS: We performed a systematic review of randomized controlled trials (RCTs) exa …
64
Effect of combined aerobic and resistance training on peak oxygen
consumption, muscle strength and health-related quality of life in patients with
heart failure with reduced left ventricular ejection fraction: a systematic review
and meta-analysis.
Gomes-Neto M, Dur.es AR, Concei..o LSR, Roever L, Silva CM, Alves IGN, Ellingsen ., Carvalho
VO.
Int J Cardiol. 2019 Oct 15;293e165-175. doi: 10.1016/j.ijcard.2019.02.050. Epub 2019 Jun 24.
PMID: 31345646
OBJECTIVE: The aim of this study was to investigate the effects of combined aerobic and resistance
training on peak oxygen consumption (peak VO(2)), minute ventilation/carbon dioxide production
(VE/VCO(2) slope), muscle strength and health-related quality of life (HRQoL) in he …
66
The impact of high-intensity inspiratory muscle training on exercise capacity
and inspiratory muscle strength in heart failure with reduced ejection fraction:
a systematic review and meta-analysis.
Gomes Neto M, Ferrari F, Helal L, Lopes AA, Carvalho VO, Stein R.
Clin Rehabil. 2018 Nov;32(11):1482-1492. doi: 10.1177/0269215518784345. Epub 2018 Jul 9.
PMID: 29984598
OBJECTIVE: Inspiratory muscle training (IMT) improves prognostic clinical variables in patients with heart failure. However, the optimal intensity for increasing those outcomes remains unclear. Thus, we aimed to determine whether high-intensity inspiratory muscle tr …
68
Effect of exercise therapy on established and emerging circulating biomarkers
in patients with heart failure: a systematic review and meta-analysis.
Pearson MJ, King N, Smart NA.
Open Heart. 2018 Jul 11;5(2):e000819. doi: 10.1136/openhrt-2018-000819. eCollection 2018.
PMID: 30018779 Free PMC article.
BACKGROUND: Biomarkers are important in the diagnosis, risk stratification and management of
patients with heart failure (HF). The established biomarkers of myocardial stretch, brain natriuretic peptide (BNP) and amino (N) portion of BNP (NT-proBNP) have been extens …
69
Impact of Exercise Programs on Hospital Readmission Following Hospitalization
for Heart Failure: A Systematic Review.
Goyal P, Delgado D, Hummel SL, Dharmarajan K.
Curr Cardiovasc Risk Rep. 2016 Oct;10(10):33. doi: 10.1007/s12170-016-0514-5. Epub 2016 Sep 9.
PMID: 28713480 Free PMC article.
Although exercise programs can improve outcomes among ambulatory heart failure patients, it is not clear whether this benefit extends to reducing readmissions following heart failure
hospitalization. We therefore conducted a systematic review of …
72
Motivational Interviewing as a Strategy to Impact Outcomes in Heart Failure
Patients: A Systematic Review.
Poudel N, Kavookjian J, Scalese MJ.
Patient. 2020 Feb;13(1):43-55. doi: 10.1007/s40271-019-00387-6.
PMID: 31502239
BACKGROUND: Heart failure (HF) hospitalization is an expensive healthcare utilization event.
...STUDY ELIGIBILITY CRITERIA, PARTICIPANTS, AND INTERVENTIONS: Randomized controlled
trials (RCTs) or controlled experimental studies published in English from January 1990 …
75
Comparison of Treadmill and Cycle Ergometer Exercise During Cardiac
Rehabilitation: A Meta-analysis.
Gerlach S, Mermier C, Kravitz L, Degnan J, Dalleck L, Zuhl M.
Arch Phys Med Rehabil. 2020 Apr;101(4):690-699. doi: 10.1016/j.apmr.2019.10.184. Epub 2019 Nov 15.
PMID: 31738893
DATA SOURCE: Databases were searched for randomized studies using single modality continuous exercise. STUDY SELECTION: Studies implemented a continuous cycling or treadmill protocol for patients with either coronary artery disease (CAD) or chronic heart failure …
76
The effect of protein and essential amino acid supplementation on muscle
strength and performance in patients with chronic heart failure: a systematic
review.
Nichols S, McGregor G, Al-Mohammad A, Ali AN, Tew G, O'Doherty AF.
Eur J Nutr. 2020 Aug;59(5):1785-1801. doi: 10.1007/s00394-019-02108-z. Epub 2019 Oct 28.
PMID: 31659450 Free PMC article. Review.
PURPOSE: Critically low skeletal muscle mass and strength, observed in 20% of people with chronic heart failure (CHF), reduces functional capacity, quality of life (QoL) and survival. ...
77
Pilates in noncommunicable diseases: A systematic review of its effects.
Miranda S, Marques A.
Complement Ther Med. 2018 Aug;39e114-130. doi: 10.1016/j.ctim.2018.05.018. Epub 2018 Jun 8.
PMID: 30012382 Review.
RESULTS: Twelve studies, mostly of moderate quality, were included with 491 participants (78.6% females; age range 13-70 years old) with breast cancer (n = 3), diabetes (n = 3), chronic stroke (2 years post stroke) (n = 2), chronic obstructive pulmonary disease (n = 1), cystic fi …
78
Key elements of interventions for heart failure patients with mild cognitive
impairment or dementia: A systematic review.
Hickman L, Ferguson C, Davidson PM, Allida S, Inglis S, Parker D, Agar M.
Eur J Cardiovasc Nurs. 2020 Jan;19(1):8-19. doi: 10.1177/1474515119865755. Epub 2019 Jul 26.
PMID: 31347402
BACKGROUND: The purpose of this systematic review was to (a) examine the effects of
interventions delivered by a heart failure professional for mild cognitive impairment and dementia on cognitive function, memory, working memory, instrumental activities of daily liv …
80
Best mode of inspiratory muscle training in heart failure patients: a systematic
review and meta-analysis.
Sadek Z, Salami A, Joumaa WH, Awada C, Ahmaidi S, Ramadan W.
Eur J Prev Cardiol. 2018 Nov;25(16):1691-1701. doi: 10.1177/2047487318792315. Epub 2018 Aug 3.
PMID: 30073849
Objectives The objective of this study was to evaluate the effects of inspiratory muscle training on inspiratory muscle strength, functional capacity and dyspnoea for patients with chronic heart
failure, by summarising the published research on the effects of inspir …
81
The Effect of Chinese Herbal Medicine on Quality of Life and Exercise Tolerance
in Heart Failure With Preserved Ejection Fraction: A Systematic Review and
Meta-Analysis of Randomized Controlled Trials.
Wang J, Yang R, Zhang F, Jia C, Wang P, Liu J, Gao K, Xie H, Wang J, Zhao H, Chen J, Wang W.
Front Physiol. 2018 Oct 26;9e1420. doi: 10.3389/fphys.2018.01420. eCollection 2018.
PMID: 30416450 Free PMC article.
Background: Chinese herbal medicine (CHM) has a good effect of alleviating symptoms and
improving quality of life and exercise tolerance in patients with heart failure with preserved
ejection fraction (HFpEF), but it wasn't sufficiently valued and promoted be …
86
Nordic walking for individuals with cardiovascular disease: A systematic review
and meta-analysis of randomized controlled trials.
Cugusi L, Manca A, Yeo TJ, Bassareo PP, Mercuro G, Kaski JC.
Eur J Prev Cardiol. 2017 Dec;24(18):1938-1955. doi: 10.1177/2047487317738592. Epub 2017 Oct
25.
PMID: 29067853 Review.
Studies focused on coronary artery disease, peripheral arterial disease, heart failure and stroke. In coronary artery disease, significant differences between NW+CCVR and CCVR were found in
exercise capacity (SMD: 0.49; p = 0.03) and dynamic balance (SMD: 0.5 …
89
Interventions to promote patient utilisation of cardiac rehabilitation.
Santiago de Ara.jo Pio C, Chaves GS, Davies P, Taylor RS, Grace SL.
Cochrane Database Syst Rev. 2019 Feb 1;2(2):CD007131. doi: 10.1002/14651858.CD007131.pub4.
PMID: 30706942 Free PMC article.
SELECTION CRITERIA: We included randomised controlled trials (RCTs) in adults with myocardial infarction, with angina, undergoing coronary artery bypass graft surgery or percutaneous coronary intervention, or with heart failure who were eligible for cardiac rehabili …
91
Hybrid versus traditional cardiac rehabilitation models: a systematic review and
meta-analysis.
Wu C, Li Y, Chen J.
Kardiol Pol. 2018;76(12):1717-1724. doi: 10.5603/KP.a2018.0175. Epub 2018 Sep 25.
PMID: 30251248 Free article.
BACKGROUND: The common drawbacks of standard cardiac rehabilitation (CR) models include low participation rate, high cost, and dependence on on-site exercise sessions. Therefore, hybrid CR protocols have been developed. AIM: We aimed to test whether hybrid CR models are su …
92
Effects of exercise on endothelial progenitor cells in patients with
cardiovascular disease: A systematic review and meta-analysis of randomized
controlled trials.
Cavalcante SL, Lopes S, Bohn L, Cavero-Redondo I, .lvarez-Bueno C, Viamonte S, Santos M,
Oliveira J, Ribeiro F.
Rev Port Cardiol. 2019 Nov;38(11):817-827. doi: 10.1016/j.repc.2019.02.016. Epub 2020 Feb 7.
PMID: 32037059 Free article. English, Portuguese.
In subgroup analyses, patients with heart failure showed a significant increase in EPCs in the
exercise training groups (ES=0.52; 95% CI: 0.15-0.90), with low heterogeneity (I(2)=0.0%;
p=0.648), while no significant increase (ES=0.67; 95% CI: -0.70-2.04; I(2) …
94
Motivational Interviewing and Self-care Practices in Adult Patients With Heart
Failure: A Systematic Review and Narrative Synthesis.
Sokalski T, Hayden KA, Raffin Bouchal S, Singh P, King-Shier K.
J Cardiovasc Nurs. 2020 Mar/Apr;35(2):107-115. doi: 10.1097/JCN.0000000000000627.
PMID: 31851149
BACKGROUND: Heart failure contributes to frequent hospitalizations, large healthcare costs, and high mortality. ...OBJECTIVE: The aim of this study was to examine the effectiveness of motivational interviewing on self-care practices in the adult population with h …
99
Involving caregivers in self-management interventions for patients with heart
failure and chronic obstructive pulmonary disease. A systematic review and
meta-analysis.
Noonan MC, Wingham J, Dalal HM, Taylor RS.
J Adv Nurs. 2019 Dec;75(12):3331-3345. doi: 10.1111/jan.14172. Epub 2019 Sep 3.
PMID: 31441088
RESULTS: Thirteen randomized controlled trials (1,701 participants: 1,439 heart failure; 262 chronic obstructive pulmonary disease) involving caregivers (mean age 59; 58% female) were identified. Reported patient health-related quality of life measures included; Min …
101
Effects of Different Telemonitoring Strategies on Chronic Heart Failure Care:
Systematic Review and Subgroup Meta-Analysis.
Ding H, Chen SH, Edwards I, Jayasena R, Doecke J, Layland J, Yang IA, Maiorana A.
J Med Internet Res. 2020 Nov 13;22(11):e20032. doi: 10.2196/20032.
PMID: 33185554 Free PMC article. Review.
BACKGROUND: Telemonitoring studies in chronic heart failure are characterized by mixed mortality and hospitalization outcomes, which have deterred the uptake of telemonitoring in clinical practice. ...These strategies should be prioritized in telemonitoring interven …
103
Targeted therapy with phosphodiesterase 5 inhibitors in patients with
pulmonary hypertension due to heart failure and elevated pulmonary vascular
resistance: a systematic review.
Sanchez Palacios GM, Schmidt C, Wichman T.
Pulm Circ. 2020 Oct 7;10(3):2045894020948780. doi: 10.1177/2045894020948780. eCollection
2020 Jul-Sep.
PMID: 33088478 Free PMC article.
Randomized clinical trials comparing Phosphodiesterase 5 inhibitors versus placebo in patients with proven Pulmonary Hypertension by right heart catheterization secondary to left heart disease (both heart failure with reduced ejection fraction and with …
104
Inspiratory Muscle Training in Patients With Heart Failure: What Is New?
Systematic Review and Meta-Analysis.
Azambuja ACM, de Oliveira LZ, Sbruzzi G.
Phys Ther. 2020 Dec 7;100(12):2099-2109. doi: 10.1093/ptj/pzaa171.
PMID: 32936904
OBJECTIVE: The benefits of inspiratory muscle training (IMT) have already been demonstrated in patients with heart failure (HF), but the best mode of training and which patients benefit from this intervention are not clear. ...Also important was establishing which t …
105
Comparison of treatment options for depression in heart failure: A network
meta-analysis.
Das A, Roy B, Schwarzer G, Silverman MG, Ziegler O, Bandyopadhyay D, Philpotts LL, Sinha S,
Blumenthal JA, Das S.
J Psychiatr Res. 2019 Jan;108e7-23. doi: 10.1016/j.jpsychires.2018.10.007. Epub 2018 Oct 25.
PMID: 30419488
BACKGROUND: Depression independently predicts poor outcomes in heart failure (HF) patients,
including increased mortality, morbidity and 30-day re-hospitalization. ...Included randomized
clinical trials (RCTs) compared interventions (Exercise therapy ( …
108
Aerobic Training Intensity for Improved Endothelial Function in Heart Failure
Patients: A Systematic Review and Meta-Analysis.
Pearson MJ, Smart NA.
Cardiol Res Pract. 2017;2017e2450202. doi: 10.1155/2017/2450202. Epub 2017 Feb 27.
PMID: 28348916 Free PMC article.
Flow-mediated dilation (FMD) is widely utilised to assess endothelial function and aerobic exercise improves FMD in heart failure patients. The aim of this meta-analysis is to quantify the effect of aerobic training intensity on FMD in patients with heart …
109
Can activity monitors predict outcomes in patients with heart failure? A
systematic review.
Tan MKH, Wong JKL, Bakrania K, Abdullahi Y, Harling L, Casula R, Rowlands AV, Athanasiou T, Jarral
OA.
Eur Heart J Qual Care Clin Outcomes. 2019 Jan 1;5(1):11-21. doi: 10.1093/ehjqcco/qcy038.
PMID: 30215706
Actigraphy is increasingly incorporated into clinical practice to monitor intervention effectiveness and patient health in congestive heart failure (CHF). We explored the prognostic impact of actigraphy-quantified physical activity (AQPA) on CHF outcomes. ...Overall …
110
Aerobic Interval vs. Continuous Training in Patients with Coronary Artery
Disease or Heart Failure: An Updated Systematic Review and Meta-Analysis
with a Focus on Secondary Outcomes.
Pattyn N, Beulque R, Cornelissen V.
Sports Med. 2018 May;48(5):1189-1205. doi: 10.1007/s40279-018-0885-5.
PMID: 29502328 Review.
We included randomized trials comparing aerobic interval training and aerobic continuous training in patients with coronary artery disease or chronic heart failure. The primary outcome was change in peak oxygen uptake. ...Aerobic interval training resulted in a high …
111
Influence of High-Intensity Interval Training Versus Continuous Training on
Functional Capacity in Individuals With Heart Failure: A SYSTEMATIC REVIEW
AND META-ANALYSIS.
Ara.jo BTS, Leite JC, Fuzari HKB, Pereira de Souza RJ, Rem.gio MI, Dornelas de Andrade A, Lima
Campos S, Cunha Brand.o D.
J Cardiopulm Rehabil Prev. 2019 Sep;39(5):293-298. doi: 10.1097/HCR.0000000000000424.
PMID: 31397766
INTRODUCTION: Cardiac rehabilitation programs reduce the risk of death and acute events related to the disease through the association of various modalities of exercise. When implemented in high-intensity interval training (HIIT) programs, it may allow for gradual adaptation.
112
Automated telephone communication systems for preventive healthcare and
management of long-term conditions.
Posadzki P, Mastellos N, Ryan R, Gunn LH, Felix LM, Pappas Y, Gagnon MP, Julious SA, Xiang L,
Oldenburg B, Car J.
Cochrane Database Syst Rev. 2016 Dec 14;12(12):CD009921. doi:
10.1002/14651858.CD009921.pub2.
PMID: 27960229 Free PMC article. Review.
BACKGROUND: Automated telephone communication systems (ATCS) can deliver voice messages and collect health-related information from patients using either their telephone's touch-tone keypad or voice recognition software. ATCS can supplement or replace telephone contact bet …
116
Combined training is the most effective training modality to improve aerobic
capacity and blood pressure control in people requiring haemodialysis for endstage
renal disease: systematic review and network meta-analysis.
Scapini KB, Bohlke M, Moraes OA, Rodrigues CG, In.cio JF, Sbruzzi G, Leguisamo CP, Sanches IC,
Tourinho Filho H, Irigoyen MC.
J Physiother. 2019 Jan;65(1):4-15. doi: 10.1016/j.jphys.2018.11.008. Epub 2018 Dec 21.
PMID: 30581137
QUESTIONS: Do aerobic, resistance and combined exercise training improve aerobic capacity,
arterial blood pressure and haemodialysis efficiency in people requiring haemodialysis for end-stage renal disease? Is one exercise training modality better than the others fo …
117
Exercise-based cardiac rehabilitation for adult patients with an implantable
cardioverter defibrillator.
Nielsen KM, Zwisler AD, Taylor RS, Svendsen JH, Lindschou J, Anderson L, Jakobsen JC, Berg SK.
Cochrane Database Syst Rev. 2019 Feb 12;2(2):CD011828. doi: 10.1002/14651858.CD011828.pub2.
PMID: 30746679 Free PMC article.
OBJECTIVES: To assess the benefits and harms of exercise-based cardiac rehabilitation
programmes (exercise-based interventions alone or in combination with psychoeducational
components) compared with control (group of no intervention, treatment as usual or another r …
119
Exercise rehabilitation in ventricular assist device recipients: a meta-analysis of
effects on physiological and clinical outcomes.
Grosman-Rimon L, Lalonde SD, Sieh N, Pakosh M, Rao V, Oh P, Grace SL.
Heart Fail Rev. 2019 Jan;24(1):55-67. doi: 10.1007/s10741-018-9695-y.
PMID: 29623546
Exercise rehabilitation in heart failure patients has been shown to improve quality of life (QoL) and survival. ...However, there have only been two meta-analyses on the effects of exercise
rehabilitation in VAD patients, on only two outcomes. The obje …
123
Tai Chi and Qigong Practices for Chronic Heart Failure: A Systematic Review
and Meta-Analysis of Randomized Controlled Trials.
Cite Chen X, Savarese G, Cai Y, Ma L, Lundborg CS, Jiang W, Wen Z, Lu W, Marrone G.
Chen X, Savarese G, Cai Y, Ma L, Lundborg CS, Jiang W, Wen Z, Lu W, Marrone G.
Evid Based Complement Alternat Med. 2020 Dec 14;2020e2034625. doi: 10.1155/2020/2034625.
eCollection 2020.
PMID: 33381195 Free PMC article.
BACKGROUND: Several randomized controlled trials (RCTs) have assessed the role of Tai Chi and Qigong Practices (TQPs) in managing chronic heart failure (CHF). They have included broad
variations in comparators, sample sizes, and results. ...CONCLUSIONS: Considering …
125
What Is the Optimal Exercise Prescription for Patients With Dilated
Cardiomyopathy in Cardiac Rehabilitation? A SYSTEMATIC REVIEW.
Seo YG, Jang MJ, Lee GY, Jeon ES, Park WH, Sung JD.
J Cardiopulm Rehabil Prev. 2019 Jul;39(4):235-240. doi: 10.1097/HCR.0000000000000382.
PMID: 31241517
PURPOSE: Dilated cardiomyopathy (DCM) is 1 of the major causes of advanced heart failure.
However, relatively little is known about the effects of exercise specifically in patients with DCM.
...Exercise type was mainly aerobic exercise and resis …
132
Depression in Somatic Disorders: Is There a Beneficial Effect of Exercise?
Roeh A, Kirchner SK, Malchow B, Maurus I, Schmitt A, Falkai P, Hasan A.
Front Psychiatry. 2019 Mar 20;10e141. doi: 10.3389/fpsyt.2019.00141. eCollection 2019.
PMID: 30949079 Free PMC article.
Background: The beneficial effects of exercise training on depressive symptoms are wellestablished. In the past years, more research attention has been drawn to the specific effects of exercise training on depressive symptoms in somatically ill patients. ...Various …
133
Physical functional performance and prognosis in patients with heart failure: a
systematic review and meta-analysis.
Fuentes-Abolafio IJ, Stubbs B, P.rez-Belmonte LM, Bernal-L.pez MR, G.mez-Huelgas R, Cuesta-
Vargas AI.
BMC Cardiovasc Disord. 2020 Dec 9;20(1):512. doi: 10.1186/s12872-020-01725-5.
PMID: 33297975 Free PMC article.
BACKGROUND: Patients with Heart Failure (HF) show impaired functional capacities which have
been related to their prognosis. ...
134
Prognostic significance of exercise-induced diastolic dysfunction: A systematic
review.
Sud K, Bhatia KS, Vogel B, Bohra C, Argulian E.
Echocardiography. 2020 Oct;37(10):1594-1602. doi: 10.1111/echo.14841. Epub 2020 Sep 5.
PMID: 32892393
METHOD: We conducted a meta-analysis to explore the prognostic significance of exerciseinduced
DD. PUBMED/EMBASE/SCOPUS databases were searched for studies reporting adverse
outcomes in patients undergoing exercise echocardiography based on diastolic response durin
135
The cost effectiveness of REACH-HF and home-based cardiac rehabilitation
compared with the usual medical care for heart failure with reduced ejection
fraction: A decision model-based analysis.
Taylor RS, Sadler S, Dalal HM, Warren FC, Jolly K, Davis RC, Doherty P, Miles J, Greaves C, Wingham J, Hillsdon M, Abraham C, Frost J, Singh S, Hayward C, Eyre V, Paul K, Lang CC, Smith K. Eur J Prev Cardiol. 2019 Aug;26(12):1252-1261. doi: 10.1177/2047487319833507. Epub 2019 Mar 18.
PMID: 30884975 Free PMC article.
BACKGROUND: The REACH-HF (Rehabilitation EnAblement in CHronic Heart Failure) trial found
that the REACH-HF home-based cardiac rehabilitation intervention resulted in a clinically meaningful improvement in disease-specific health-related quality of life in patients …
136
Supervised exercise training versus usual care in ambulatory patients with left
ventricular assist devices: A systematic review.
Ganga HV, Leung A, Jantz J, Choudhary G, Stabile L, Levine DJ, Sharma SC, Wu WC.
PLoS One. 2017 Mar 31;12(3):e0174323. doi: 10.1371/journal.pone.0174323. eCollection 2017.
PMID: 28362876 Free PMC article. Review.
Implantation of left ventricular assist devices (LVAD) has increased because of improved safety
profile and limited availability of heart transplantation. Although supervised exercise training (ET) programs are known to improve exercise capacity and quality o …
137
The Efficacy of Psychological Interventions on Health-Related Quality of Life for
Patients with Heart Failure and Depression: A Systematic Review.
Helal SI, Lee G, Evans C, Grealish A.
J Cardiovasc Nurs. 2020 Dec 29;Publish Ahead of Print. doi: 10.1097/JCN.0000000000000779.
Online ahead of print.
PMID: 33394624
BACKGROUND: Depression is prevalent among adults with chronic heart failure (CHF) and is
associated with higher rates of morbidity and mortality and higher healthcare costs. ...Study authors sampled 757 participants and evaluated 4 psychological interventions: cogni …
141
The effect of Tai Chi on four chronic conditions-cancer, osteoarthritis, heart
failure and chronic obstructive pulmonary disease: a systematic review and
meta-analyses.
Chen YW, Hunt MA, Campbell KL, Peill K, Reid WD.
Br J Sports Med. 2016 Apr;50(7):397-407. doi: 10.1136/bjsports-2014-094388. Epub 2015 Sep 17.
PMID: 26383108 Review.
The aim of this systematic review was to summarise current evidence regarding the effectiveness of Tai Chi in individuals with four common chronic conditions-cancer, osteoarthritis (OA), heart failure
(HF) and chronic obstructive pulmonary disease (COPD). ...CONCLUS …
142
Effect of High-Intensity Interval Training on Aerobic Capacity and Heart Rate
Control of Heart Transplant Recipients: a Systematic Review with Meta-
Analysis.
Concei..o LSR, Gois CO, Fernandes RES, Martins-Filho PRS, Gomes M Neto, Neves VR, Carvalho
VO. Braz J Cardiovasc Surg. 2020 Oct 28. doi: 10.21470/1678-9741-2019-0420. Online ahead of print.
PMID: 33113314
INTRODUCTION: Heart transplantation (HTx) is the gold standard procedure for selected individuals with refractory heart failure. ...The primary aim of this study was to perform a systematic review and meta-analysis about the effect of HIIT compared to MICT on …
143
Safety and Efficacy of Exercise Training in Patients With an Implantable
Cardioverter-Defibrillator: A Meta-Analysis.
Pandey A, Parashar A, Moore C, Ngo C, Salahuddin U, Bhargava M, Kumbhani DJ, Piccini JP,
Fonarow GC, Berry JD.
JACC Clin Electrophysiol. 2017 Feb;3(2):117-126. doi: 10.1016/j.jacep.2016.06.008. Epub 2016 Sep 7.
PMID: 29759383
OBJECTIVES: In this study, the authors performed a meta-analysis of currently available
comparative prospective studies to assess the efficacy and safety of exercise training in heart
failure (HF) patients with implantable cardioverter-defibrillators (ICD). . …
149
Cardiac Rehabilitation in Patients With Left Ventricular Assist Device: A
SYSTEMATIC REVIEW AND META-ANALYSIS.
Mahfood Haddad T, Saurav A, Smer A, Azzouz MS, Akinapelli A, Williams MA, Alla VM.
J Cardiopulm Rehabil Prev. 2017 Nov;37(6):390-396. doi: 10.1097/HCR.0000000000000254.
PMID: 28727672 Review.
PURPOSE: Exercise-based cardiac rehabilitation (EBCR) has been demonstrated to improve
functional capacity in heart failure (HF). ...METHODS: PubMed, Web of Science, CINAHL, and
Cochrane Library databases were searched for randomized studies assessing the imp …
153
Behaviour change techniques in home-based cardiac rehabilitation: a
systematic review.
Heron N, Kee F, Donnelly M, Cardwell C, Tully MA, Cupples ME.
Br J Gen Pract. 2016 Oct;66(651):e747-57. doi: 10.3399/bjgp16X686617. Epub 2016 Aug 1.
PMID: 27481858 Free PMC article. Review.
RESULTS: From 2448 studies identified, 11 of good methodological quality (10 on post-myocardial infarction, one on heart failure, 1907 patients) were included. These reported the use of 20 different BCTs. ...
160
can occur immediately after immersion. Combination of water immersion, cold ex …
169
Effects of High-Intensity Interval Training on Aerobic Capacity in Cardiac
Patients: A Systematic Review with Meta-Analysis.
Xie B, Yan X, Cai X, Li J.
Biomed Res Int. 2017;2017e5420840. doi: 10.1155/2017/5420840. Epub 2017 Mar 12.
PMID: 28386556 Free PMC article. Review.
No significant difference between the INTERVAL and CONTINUOUS groups was observed in terms of peak heart rate, peak minute ventilation, VE/VCO(2) slope and respiratory exchange ratio, body mass, systolic or diastolic blood pressure, triglyceride or low- or high-density lip …
170
Buckingham SA, Taylor RS, Jolly K, Zawada A, Dean SG, Cowie A, Norton RJ, Dalal HM.Open Heart. 2016 Sep 14;3(2):e000463. doi: 10.1136/openhrt-2016-000463. eCollection 2016.PMID: 27738516 Free PMC article.
Randomised trials comparing home-based and centre-based CR programmes in adults with myocardial infarction, angina, heart failure or who had undergone coronary revascularisation were included. ...CONCLUSIONS: Home-based and centre-based CR provide similar benefits i …
173
Effect of exergaming on health-related quality of life in older adults: A systematic review.
Cacciata M, Stromberg A, Lee JA, Sorkin D, Lombardo D, Clancy S, Nyamathi A, Evangelista LS.Int J Nurs Stud. 2019 May;93:30-40. doi: 10.1016/j.ijnurstu.2019.01.010. Epub 2019 Feb 10.PMID: 30861452
INTRODUCTION: Exercise through video or virtual reality games (i.e. exergames) has grown in popularity among older adults; however, there is limited evidence on efficacy of exergaming on well-being related to health in this population. ...The study participants, exergaming …
Exercise therapy for people with Angina
METHOD
The National Library of Medicine www.nlm.govwas searched for ‘Systematic Review’, in the last 5 years. 28 reviews were identified.
These were reviewed by Muir Gray for relevance eg some systematic reviews were focused on drug therapy, this removed 18 reviews from the database and the remaining 10 are listed below.
USING THE DATABASE
To read the abstract or the full text simple copy the doi, for example
doi: 10.1016/j.bjpt.2017.06.004. and paste it into your web browser
1
Exercise-based cardiac rehabilitation for adults with stable angina.
Long L, Anderson L, Dewhirst AM, He J, Bridges C, Gandhi M, Taylor RS.
Cochrane Database Syst Rev. 2018 Feb 2;2(2):CD012786. doi: 10.1002/14651858.CD012786.pub2.
PMID: 29394453 Free PMC article. Review.
OBJECTIVES: To assess the effects of exercise-based CR compared to usual care for adults with stable angina. ...Low-quality evidence indicates that exercise-based CR may result in a small increase in exercise capacity compared to usual care. ...
2
Exercise-based cardiac rehabilitation for stable angina: systematic review and
meta-analysis.
Long L, Anderson L, He J, Gandhi M, Dewhirst A, Bridges C, Taylor R.
Open Heart. 2019 Jun 5;6(1):e000989. doi: 10.1136/openhrt-2018-000989. eCollection 2019.
PMID: 31245012 Free PMC article.
OBJECTIVE: A systematic review was undertaken to assess the effects of exercise-based cardiac rehabilitation (CR) for patients with stable angina. ...No data were identified on cost-effectiveness or return to work. CONCLUSIONS: Exercise-based CR may improve t …
5
Effects of Exercise after Percutaneous Coronary Intervention on Cardiac
Function and Cardiovascular Adverse Events in Patients with Coronary Heart
Disease: Systematic Review and Meta-Analysis.
Zhang H, Chang R.
J Sports Sci Med. 2019 Jun 1;18(2):213-222. eCollection 2019 Jun.
PMID: 31191090 Free PMC article.
Left ventricular end diastolic diameter (LVEDD), left ventricular ejection fraction (LVEF), 6-minute
walking distance (6MWD), cardiac death, myocardial infarction, coronary angioplasty, coronary
artery bypass surgery (CABG), and angina pectoris or restenosis per ran …
6
Home-based versus centre-based cardiac rehabilitation.
Anderson L, Sharp GA, Norton RJ, Dalal H, Dean SG, Jolly K, Cowie A, Zawada A, Taylor RS.
Cochrane Database Syst Rev. 2017 Jun 30;6(6):CD007130. doi: 10.1002/14651858.CD007130.pub4.
PMID: 28665511 Free PMC article. Review.
OBJECTIVES: To compare the effect of home-based and supervised centre-based cardiac
rehabilitation on mortality and morbidity, exercise-capacity, health-related quality of life, and
modifiable cardiac risk factors in patients with heart disease. ...Trials were generally of …
8
Cardiac Rehabilitation and Exercise Prescription in Symptomatic Patients with
Non-Obstructive Coronary Artery Disease-a Systematic Review.
Kissel CK, Nikoletou D.
Curr Treat Options Cardiovasc Med. 2018 Aug 18;20(9):78. doi: 10.1007/s11936-018-0667-2.
PMID: 30121850 Free PMC article. Review.
Treatment is empiric, and 30% of patients remain symptomatic in spite of therapy. It is well known that physical exercise can improve endothelial function. ...Most patients were women (97.7%). Exercise programs varied from 8 weeks to 4 months at moderate inte …
9
Refractory angina is a growing challenge for palliative medicine: a systematic
review of non-invasive interventions.
Murphy I, Sivashankar A, Gadoud A.
BMJ Support Palliat Care. 2020 Jun 4:bmjspcare-2020-002202. doi: 10.1136/bmjspcare-2020-
002202. Online ahead of print.
PMID: 32499404 Review.
BACKGROUND: Refractory angina can have a significant effect on quality of life. Non-invasive
interventions have been suggested but there are few guidelines on management. ...CONCLUSION:
There are non-invasive treatments for refractory angina that are overlooked by c …
12
Spinal Cord Stimulation for Refractory Angina Pectoris: A Systematic Review
and Meta-analysis.
Pan X, Bao H, Si Y, Xu C, Chen H, Gao X, Xie X, Xu Y, Sun F, Zeng L.
Clin J Pain. 2017 Jun;33(6):543-551. doi: 10.1097/AJP.0000000000000435.
PMID: 27875377 Free PMC article. Review.
The aim of this meta-analysis was to evaluate the efficacy and safety of conventional spinal cord stimulation (SCS) in the treatment of refractory angina pectoris (RAP). MATERIALS AND
METHODS: Relevant randomized controlled trials that investigated SCS for patients …
14
Interventions to promote patient utilisation of cardiac rehabilitation.
Santiago de Ara.jo Pio C, Chaves GS, Davies P, Taylor RS, Grace SL.
Cochrane Database Syst Rev. 2019 Feb 1;2(2):CD007131. doi: 10.1002/14651858.CD007131.pub4.
PMID: 30706942 Free PMC article.
We searched the Cochrane Central Register of Controlled Trials (CENTRAL); the National Health
Service (NHS) Centre for Reviews and Dissemination (CRD) databases (Health Technology
Assessment (HTA) and Database of Abstracts of Reviews of Effects (DARE)), in the Cochrane
Library (W …
25
Neuromuscular electrical stimulation of the thighs in cardiac patients with
implantable cardioverter defibrillators.
Cenik F, Schoberwalter D, Keilani M, Maehr B, Wolzt M, Marhold M, Crevenna R.
Wien Klin Wochenschr. 2016 Nov;128(21-22):802-808. doi: 10.1007/s00508-016-1045-2. Epub
2016 Jul 25.
PMID: 27457876 Free PMC article. Review.
BACKGROUND: The aim of this systematic review was to update scientific knowledge concerning the safety of neuromuscular electrical stimulation (NMES) to increase exercise capacity and prevent cardiac cachexia in patients with implantable cardioverter defibrillators
26
Effect of Mobile Health Interventions on the Secondary
27
The Effect of Cardiac Rehabilitation on Health-Related Quality of Life in Patients
With Coronary Artery Disease: A Meta-analysis.
Francis T, Kabboul N, Rac V, Mitsakakis N, Pechlivanoglou P, Bielecki J, Alter D, Krahn M.
Can J Cardiol. 2019 Mar;35(3):352-364. doi: 10.1016/j.cjca.2018.11.013. Epub 2018 Nov 24.
PMID: 30825955
RCTs included adult patients with diagnosed coronary artery disease via angiography, myocardial
infarction, angina, or who had undergone coronary revascularization. The Cochrane Library,
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